{"created":"2023-08-02T03:57:59.025802+00:00","id":7103,"links":{},"metadata":{"_buckets":{"deposit":"26d11ad4-4572-4978-a73a-f56bfe07caf8"},"_deposit":{"created_by":10,"id":"7103","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"7103"},"status":"published"},"_oai":{"id":"oai:repository.lib.tottori-u.ac.jp:00007103","sets":["1:9","2:12"]},"author_link":["4942","369","2504","405","3674","26280","26281"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"1192","bibliographicPageStart":"1189","bibliographicVolumeNumber":"48","bibliographic_titles":[{"bibliographic_title":"Auris Nasus Larynx"},{"bibliographic_title":"Auris Nasus Larynx","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Basaloid squamous cell carcinoma (BSCC), a histologically distinctive variant of squamous cell carcinoma comprising basal cell carcinoma and squamous cell carcinoma, is aggressive and shows a poor prognosis because of frequent lymph node invasion and distant metastases. To date few articles regarding chemotherapy for metastatic disease have been reported, thus feasible chemotherapy is not well established. Cetuximab is a monoclonal antibody for epithelial growth factor receptor (EGFR), which has great efficacy for head and neck squamous cell carcinoma due to EGFR signaling pathway blockage. Because BSCC also highly expresses EGFR, cetuximab may be effective for BSCC. We report here a first case of recurrent BSCC in the ethmoid sinus with intracranial extension treated with cetuximab-based chemotherapy, which revealed great response in a 40-year-old man. Positron emission tomography (PET) revealed no lymph node or distant metastasis. The patient underwent chemoradiotherapy 66 Gy in 33 fractions with triweekly 100 mg/m2 cisplatin. However, 12 weeks after treatment completion PET revealed a residual tumor at the primary cancer site. Combination therapy with weekly paclitaxel and cetuximab was started, and complete response was observed 2 months from treatment initiation. The patient has maintained complete response for 32 months, and no tumor regrowth has been observed.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier B.V."}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.anl.2020.07.002","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Koyama, Satoshi. Fujiwara, Kazunori. Morisaki, Tsuyoshi. et al. Cetuximab and paclitaxel combination therapy for recurrent basaloid squamous cell carcinoma in the ethmoid sinus. Auris Nasus Larynx. 48(6), 1189-1192. 2020-07-16."}]}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://www.sciencedirect.com/science/article/pii/S0385814620301590"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.sciencedirect.com/science/article/pii/S0385814620301590","subitem_relation_type_select":"URI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2020 Oto-Rhino-Laryngological Society of Japan Inc. Published by Elsevier B.V. All rights reserved."}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03858146","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_33":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine"},{"subitem_text_language":"en","subitem_text_value":"Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine"},{"subitem_text_language":"en","subitem_text_value":"Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine"},{"subitem_text_language":"en","subitem_text_value":"Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine / Center for Head and Neck Surgery, Kusatsu General Hospital"},{"subitem_text_language":"en","subitem_text_value":"Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine"},{"subitem_text_language":"en","subitem_text_value":"Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine"},{"subitem_text_language":"en","subitem_text_value":"Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小山, 哲史"},{"creatorName":"コヤマ, サトシ","creatorNameLang":"ja-Kana"},{"creatorName":"Koyama, Satoshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4942","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"100002206","nameIdentifierScheme":"研究者総覧鳥取大学","nameIdentifierURI":"http://researchers.adm.tottori-u.ac.jp/html/100002206_ja.html"}]},{"creatorNames":[{"creatorName":"藤原, 和典"},{"creatorName":"フジワラ, カズノリ","creatorNameLang":"ja-Kana"},{"creatorName":"Fujiwara, Kazunori","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"369","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"90403419","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=90403419"},{"nameIdentifier":"100000417","nameIdentifierScheme":"研究者総覧鳥取大学","nameIdentifierURI":"http://researchers.adm.tottori-u.ac.jp/html/100000417_ja.html"}]},{"creatorNames":[{"creatorName":"中村, 陽祐"},{"creatorName":"ナカムラ, ヨウスケ","creatorNameLang":"ja-Kana"},{"creatorName":"Nakamura, Yosuke","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2504","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"70403417","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=70403417"},{"nameIdentifier":"100001307","nameIdentifierScheme":"研究者総覧鳥取大学","nameIdentifierURI":"http://researchers.adm.tottori-u.ac.jp/html/100001307_ja.html"}]},{"creatorNames":[{"creatorName":"福原, 隆宏"},{"creatorName":"フクハラ, タカヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"Fukuhara, Takahiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"405","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"80403418","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=80403418"},{"nameIdentifier":"100001318","nameIdentifierScheme":"研究者総覧鳥取大学","nameIdentifierURI":"http://researchers.adm.tottori-u.ac.jp/html/100001318_ja.html"}]},{"creatorNames":[{"creatorName":"竹内, 裕美"},{"creatorName":"タケウチ, ヒロミ","creatorNameLang":"ja-Kana"},{"creatorName":"Takeuchi, Hiromi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3674","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"40197273","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=40197273"},{"nameIdentifier":"100000179","nameIdentifierScheme":"研究者総覧鳥取大学","nameIdentifierURI":"http://researchers.adm.tottori-u.ac.jp/html/100000179_ja.html"}]},{"creatorNames":[{"creatorName":"Morisaki, Tsuyoshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"26280","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fujii, Taihei","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"26281","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-01-01"}],"displaytype":"detail","filename":"anl48(6)_1189.pdf","filesize":[{"value":"482.8 kB"}],"format":"application/pdf","licensefree":"© 2020 Oto-Rhino-Laryngological Society of Japan Inc. Published by Elsevier B.V. All rights reserved.","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"anl48(6)_1189.pdf","url":"https://repository.lib.tottori-u.ac.jp/record/7103/files/anl48(6)_1189.pdf"},"version_id":"b35c7fba-bec4-4103-8cd3-4cae428a9fb9"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Basaloid squamous cell carcinoma","subitem_subject_scheme":"Other"},{"subitem_subject":"Cetuximab","subitem_subject_scheme":"Other"},{"subitem_subject":"Head and neck","subitem_subject_scheme":"Other"},{"subitem_subject":"Metastasis","subitem_subject_scheme":"Other"},{"subitem_subject":"Chemotherapy","subitem_subject_scheme":"Other"},{"subitem_subject":"Basaloid squamous cell carcinoma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Cetuximab","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Head and neck","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Metastasis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Chemotherapy","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Cetuximab and paclitaxel combination therapy for recurrent basaloid squamous cell carcinoma in the ethmoid sinus","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Cetuximab and paclitaxel combination therapy for recurrent basaloid squamous cell carcinoma in the ethmoid sinus","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"10","path":["12","9"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-12-15"},"publish_date":"2021-12-15","publish_status":"0","recid":"7103","relation_version_is_last":true,"title":["Cetuximab and paclitaxel combination therapy for recurrent basaloid squamous cell carcinoma in the ethmoid sinus"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2023-11-22T01:45:34.485104+00:00"}