{"created":"2023-08-02T03:57:59.091699+00:00","id":7104,"links":{},"metadata":{"_buckets":{"deposit":"e202e078-e1fe-4056-a223-7f49be6be36b"},"_deposit":{"created_by":10,"id":"7104","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"7104"},"status":"published"},"_oai":{"id":"oai:repository.lib.tottori-u.ac.jp:00007104","sets":["1:9","2:12"]},"author_link":["4942","369","2191","405","3674","26282"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"165","bibliographicPageStart":"161","bibliographicVolumeNumber":"48","bibliographic_titles":[{"bibliographic_title":"Auris Nasus Larynx"},{"bibliographic_title":"Auris Nasus Larynx","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ObjectiveThe increase in treatment options resulted in successful treatment with multiple lines of chemotherapy for recurrent and metastatic (RM) head and neck cancer (HNC). The present study aimed to elucidate the beneficial effect of successive treatment for RM-HNC. MethodsWe included 78 patients with RM-HNC who received one or multiple lines of chemotherapy from January 2008 to December 2019. We divided the patients into three groups according to treatment period: January 2008 to November 2012 included those who underwent cancer chemotherapy only with cytotoxic agents (Tox group), December 2012 to March 2017 included those who received cytotoxic agents and cetuximab (Cet group), and March 2017 to December 2019 included those who received cytotoxic agents, cetuximab and immune checkpoint inhibitor nivolumab (Nivo group). Moreover, we compared the overall survival of the three groups. ResultsIn total, 18, 33, and 27 patients were included in the Tox, Cet, and Nivo groups, respectively. The median overall survival were 8.5 months in the Tox group, 16 months in the Cet group, and 19 months in the Nivo group, and the difference in the result was significant. ConclusionsSuccessive treatment with second and subsequent lines of chemotherapy in patients with RM-HNC improves prognosis.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier B.V."}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.anl.2020.07.016","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Koyama, Satoshi. Fujiwara, Kazunori. Morisaki, Tsuyoshi. et al. Efficacy of second and subsequent lines of chemotherapy for recurrent and metastatic head and neck cancer. Auris Nasus Larynx. 2021. 48(1), 161-165."}]}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://www.sciencedirect.com/science/article/pii/S0385814620301978"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.sciencedirect.com/science/article/pii/S0385814620301978","subitem_relation_type_select":"URI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2020 Oto-Rhino-Laryngological Society of Japan Inc. Published by Elsevier B.V. All rights reserved."}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03858146","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_33":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine"},{"subitem_text_language":"en","subitem_text_value":"Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine"},{"subitem_text_language":"en","subitem_text_value":"Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine"},{"subitem_text_language":"en","subitem_text_value":"Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine"},{"subitem_text_language":"en","subitem_text_value":"Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine"},{"subitem_text_language":"en","subitem_text_value":"Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小山, 哲史"},{"creatorName":"コヤマ, サトシ","creatorNameLang":"ja-Kana"},{"creatorName":"Koyama, Satoshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4942","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"100002206","nameIdentifierScheme":"研究者総覧鳥取大学","nameIdentifierURI":"http://researchers.adm.tottori-u.ac.jp/html/100002206_ja.html"}]},{"creatorNames":[{"creatorName":"藤原, 和典"},{"creatorName":"フジワラ, カズノリ","creatorNameLang":"ja-Kana"},{"creatorName":"Fujiwara, Kazunori","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"369","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"90403419","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=90403419"},{"nameIdentifier":"100000417","nameIdentifierScheme":"研究者総覧鳥取大学","nameIdentifierURI":"http://researchers.adm.tottori-u.ac.jp/html/100000417_ja.html"}]},{"creatorNames":[{"creatorName":"三宅, 成智"},{"creatorName":"ミヤケ, ナリトモ","creatorNameLang":"ja-Kana"},{"creatorName":"Miyake, Naritomo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2191","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60464278","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=60464278"},{"nameIdentifier":"100001499","nameIdentifierScheme":"研究者総覧鳥取大学","nameIdentifierURI":"http://researchers.adm.tottori-u.ac.jp/html/100001499_ja.html"}]},{"creatorNames":[{"creatorName":"福原, 隆宏"},{"creatorName":"フクハラ, タカヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"Fukuhara, Takahiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"405","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"80403418","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=80403418"},{"nameIdentifier":"100001318","nameIdentifierScheme":"研究者総覧鳥取大学","nameIdentifierURI":"http://researchers.adm.tottori-u.ac.jp/html/100001318_ja.html"}]},{"creatorNames":[{"creatorName":"竹内, 裕美"},{"creatorName":"タケウチ, ヒロミ","creatorNameLang":"ja-Kana"},{"creatorName":"Takeuchi, Hiromi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3674","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"40197273","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=40197273"},{"nameIdentifier":"100000179","nameIdentifierScheme":"研究者総覧鳥取大学","nameIdentifierURI":"http://researchers.adm.tottori-u.ac.jp/html/100000179_ja.html"}]},{"creatorNames":[{"creatorName":"Morisaki, Tsuyoshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"26282","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-03-01"}],"displaytype":"detail","filename":"anl48(1)_161.pdf","filesize":[{"value":"592.7 kB"}],"format":"application/pdf","licensefree":"© 2020 Oto-Rhino-Laryngological Society of Japan Inc. Published by Elsevier B.V. All rights reserved.","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"anl48(1)_161.pdf","url":"https://repository.lib.tottori-u.ac.jp/record/7104/files/anl48(1)_161.pdf"},"version_id":"390d9bd4-e07a-406f-8b2b-7bb47ea91277"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Recurrent and metastatic","subitem_subject_scheme":"Other"},{"subitem_subject":"Head and neck cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"Second-line","subitem_subject_scheme":"Other"},{"subitem_subject":"Successive","subitem_subject_scheme":"Other"},{"subitem_subject":"Chemotherapy","subitem_subject_scheme":"Other"},{"subitem_subject":"Recurrent and metastatic","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Head and neck cancer","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Second-line","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Successive","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Chemotherapy","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Efficacy of second and subsequent lines of chemotherapy for recurrent and metastatic head and neck cancer","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Efficacy of second and subsequent lines of chemotherapy for recurrent and metastatic head and neck cancer","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"10","path":["12","9"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-12-15"},"publish_date":"2021-12-15","publish_status":"0","recid":"7104","relation_version_is_last":true,"title":["Efficacy of second and subsequent lines of chemotherapy for recurrent and metastatic head and neck cancer"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2023-11-22T01:45:39.212869+00:00"}