{"created":"2023-08-02T03:58:03.835542+00:00","id":7197,"links":{},"metadata":{"_buckets":{"deposit":"01330265-88e0-41ff-a681-235e8819c0ea"},"_deposit":{"created_by":10,"id":"7197","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"7197"},"status":"published"},"_oai":{"id":"oai:repository.lib.tottori-u.ac.jp:00007197","sets":["1:9","2:12"]},"author_link":["4675","4886","26649","26650","26651","26652","26653","26654","26655","26656"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-04-16","bibliographicIssueDateType":"Issued"},"bibliographicVolumeNumber":"15","bibliographic_titles":[{"bibliographic_title":"FRONTIERS IN NEURAL CIRCUITS"},{"bibliographic_title":"FRONTIERS IN NEURAL CIRCUITS","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Monocular deprivation (MD) of vision during early postnatal life induces amblyopia, and most neurons in the primary visual cortex lose their responses to the closed eye. Anatomically, the somata of neurons in the closed-eye recipient layer of the lateral geniculate nucleus (LGN) shrink and their axons projecting to the visual cortex retract. Although it has been difficult to restore visual acuity after maturation, recent studies in rodents and cats showed that a period of exposure to complete darkness could promote recovery from amblyopia induced by prior MD. However, in cats, which have an organization of central visual pathways similar to humans, the effect of dark rearing only improves monocular vision and does not restore binocular depth perception. To determine whether dark rearing can completely restore the visual pathway, we examined its effect on the three major concomitants of MD in individual visual neurons, eye preference of visual cortical neurons and soma size and axon morphology of LGN neurons. Dark rearing improved the recovery of visual cortical responses to the closed eye compared with the recovery under binocular conditions. However, geniculocortical axons serving the closed eye remained retracted after dark rearing, whereas reopening the closed eye restored the soma size of LGN neurons. These results indicate that dark rearing incompletely restores the visual pathway, and thus exerts a limited restorative effect on visual function.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Frontiers Media"}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.3389/fncir.2021.637638","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Gotou Takahiro, Kameyama Katsuro, Kobayashi Ayane, et al. Dark Rearing Promotes the Recovery of Visual Cortical Responses but Not the Morphology of Geniculocortical Axons in Amblyopic Cat. FRONTIERS IN NEURAL CIRCUITS. 2021. 15. doi:10.3389/fncir.2021.637"}]}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://www.frontiersin.org/articles/10.3389/fncir.2021.637638/full"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.frontiersin.org/articles/10.3389/fncir.2021.637638/full","subitem_relation_type_select":"URI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright © 2021 Gotou, Kameyama, Kobayashi, Okamura, Ando, Terata, Yamada, Ohta, Morizane and Hata. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in o"}]},"item_10001_text_26":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_text_value":"16625110"}]},"item_10001_text_33":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Division of Integrative Bioscience, Tottori University Graduate School of Medical Sciences"},{"subitem_text_language":"en","subitem_text_value":"Division of Integrative Bioscience, Tottori University Graduate School of Medical Sciences / Division of Neuroscience, School of Life Science, Faculty of Medicine, Tottori University"},{"subitem_text_language":"en","subitem_text_value":"Division of Integrative Bioscience, Tottori University Graduate School of Medical Sciences"},{"subitem_text_language":"en","subitem_text_value":"Division of Integrative Bioscience, Tottori University Graduate School of Medical Sciences"},{"subitem_text_language":"en","subitem_text_value":"Division of Neuroscience, School of Life Science, Faculty of Medicine, Tottori University"},{"subitem_text_language":"en","subitem_text_value":"Division of Integrative Bioscience, Tottori University Graduate School of Medical Sciences"},{"subitem_text_language":"en","subitem_text_value":"Division of Integrative Bioscience, Tottori University Graduate School of Medical Sciences"},{"subitem_text_language":"en","subitem_text_value":"Division of Integrative Bioscience, Tottori University Graduate School of Medical Sciences"},{"subitem_text_language":"en","subitem_text_value":"Division of Neuroscience, School of Life Science, Faculty of Medicine, Tottori University"},{"subitem_text_language":"en","subitem_text_value":"Division of Integrative Bioscience, Tottori University Graduate School of Medical Sciences / Division of Neuroscience, School of Life Science, Faculty of Medicine, Tottori University"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"カメヤマ, カツロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Kameyama, Katsuro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4675","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"80446517","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=80446517"},{"nameIdentifier":"100000297","nameIdentifierScheme":"研究者総覧鳥取大学","nameIdentifierURI":"http://researchers.adm.tottori-u.ac.jp/html/100000297_ja.html"}]},{"creatorNames":[{"creatorName":"畠, 義郎"},{"creatorName":"ハタ, ヨシオ","creatorNameLang":"ja-Kana"},{"creatorName":"Hata, Yoshio","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4886","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"40212146","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=40212146"},{"nameIdentifier":"100000306","nameIdentifierScheme":"研究者総覧鳥取大学","nameIdentifierURI":"http://researchers.adm.tottori-u.ac.jp/html/100000306_ja.html"}]},{"creatorNames":[{"creatorName":"Gotou, Takahiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"26649","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kobayashi, Ayane","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"26650","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Okamura, Kayoko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"26651","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ando, Takahiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"26652","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Terata, Keiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"26653","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamada, Chihiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"26654","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ohta, Hiroyuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"26655","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Morizane, Ayaka","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"26656","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-03-17"}],"displaytype":"detail","filename":"fnc15_fncir_2021_637638.pdf","filesize":[{"value":"1.6 MB"}],"format":"application/pdf","licensefree":"Copyright © 2021 Gotou, Kameyama, Kobayashi, Okamura, Ando, Terata, Yamada, Ohta, Morizane and Hata. 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