{"created":"2023-08-02T03:58:06.312875+00:00","id":7251,"links":{},"metadata":{"_buckets":{"deposit":"bd0b9bc9-888f-4025-94eb-e26db889895c"},"_deposit":{"created_by":10,"id":"7251","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"7251"},"status":"published"},"_oai":{"id":"oai:repository.lib.tottori-u.ac.jp:00007251","sets":["1:9","2:12"]},"author_link":["26903","4733","4524","26904","26905"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"11","bibliographicPageEnd":"1267","bibliographicPageStart":"1262","bibliographicVolumeNumber":"44","bibliographic_titles":[{"bibliographic_title":"JOURNAL OF DERMATOLOGY"},{"bibliographic_title":"JOURNAL OF DERMATOLOGY","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Neurofibromatosis 1 (NF1) is a genetic disease characterized by cutaneous, neurological and osseous complications. Although clinical manifestations of NF1 are variable, there has been no report on evaluation of severity in patients with NF1. To elucidate the grade of severity of NF1, a retrospective study was conducted in 124 NF1 patients at the Department of Dermatology of Tottori University Hospital in 2007–2016. The DNB classification (dermatological, neurological and bone manifestations) in Japan was used for assessment. Based on our current epidemiological data, there were 55 patients (44.3%) in stage 1, 23 (18.6%) in stage 2, three (2.4%) in stage 3, one (0.8%) in stage 4 and 42 (33.9%) in stage 5. The grade of severity in patients with NF1 tended to be higher with aging. Remarkably, 61.8% of the patients in stage 5 had diffuse plexiform neurofibromas with functional disability. We should pay attention to diffuse plexiform neurofibromas that greatly affect quality of life in patients with NF1.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"WILEY"}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1111/1346-8138.13902","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Ehara Yuko, Yamamoto Osamu, Kosaki Kenjiro, et al. Clinical severity in Japanese patients with neurofibromatosis 1 based on DNB classification. JOURNAL OF DERMATOLOGY. 2017. 44(11). 1262-1267. doi:10.1111/1346-8138.13902"}]}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://onlinelibrary.wiley.com/doi/10.1111/1346-8138.13902"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://onlinelibrary.wiley.com/doi/10.1111/1346-8138.13902","subitem_relation_type_select":"URI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"(C) 2017 Japanese Dermatological Association"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00696658","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03852407","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_26":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_text_value":"13468138"}]},"item_10001_text_33":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Division of Dermatology, Department of Medicine of Sensory and Motor Organs, Faculty of Medicine,Tottori University"},{"subitem_text_language":"en","subitem_text_value":"Division of Dermatology, Department of Medicine of Sensory and Motor Organs, Faculty of Medicine, Tottori University"},{"subitem_text_language":"en","subitem_text_value":"Center for Medical Genetics, Keio University School of Medicine"},{"subitem_text_language":"en","subitem_text_value":"Division of Dermatology, Department of Medicine of Sensory and Motor Organs, Faculty of Medicine, Tottori University"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"江原, 由布子"},{"creatorName":"エハラ, ユウコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山元, 修"},{"creatorName":"ヤマモト, オサム","creatorNameLang":"ja-Kana"},{"creatorName":"Yamamoto, Osamu","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"吉田, 雄一"},{"creatorName":"ヨシダ, ユウイチ","creatorNameLang":"ja-Kana"},{"creatorName":"Yoshida, Yuichi","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Ehara, Yuko","creatorNameLang":"en"},{"creatorName":"エハラ, ユウコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kosaki, Kenjiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-03-17"}],"displaytype":"detail","filename":"jd44(11)_1262.pdf","filesize":[{"value":"1.1 MB"}],"format":"application/pdf","licensefree":"(C) 2017 Japanese Dermatological Association","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"jd44(11)_1262.pdf","url":"https://repository.lib.tottori-u.ac.jp/record/7251/files/jd44(11)_1262.pdf"},"version_id":"b7abb2aa-c91f-4331-872a-73b5eeadda69"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"clinical severity","subitem_subject_scheme":"Other"},{"subitem_subject":"diffuse plexiform neurofibromas","subitem_subject_scheme":"Other"},{"subitem_subject":"DNB classification","subitem_subject_scheme":"Other"},{"subitem_subject":"neurofibromatosis 1","subitem_subject_scheme":"Other"},{"subitem_subject":"quality of life","subitem_subject_scheme":"Other"},{"subitem_subject":"clinical severity","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"diffuse plexiform neurofibromas","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"DNB classification","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"neurofibromatosis 1","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"quality of life","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article"}]},"item_title":"Clinical severity in Japanese patients with neurofibromatosis 1 based on DNB classification","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Clinical severity in Japanese patients with neurofibromatosis 1 based on DNB classification","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"10","path":["12","9"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-03-09"},"publish_date":"2021-03-09","publish_status":"0","recid":"7251","relation_version_is_last":true,"title":["Clinical severity in Japanese patients with neurofibromatosis 1 based on DNB classification"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2023-11-22T01:48:36.714254+00:00"}