{"created":"2023-08-02T03:58:09.818107+00:00","id":7316,"links":{},"metadata":{"_buckets":{"deposit":"41f60964-8aab-46e8-8781-3d575c4e8e4f"},"_deposit":{"created_by":10,"id":"7316","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"7316"},"status":"published"},"_oai":{"id":"oai:repository.lib.tottori-u.ac.jp:00007316","sets":["1:9","2:12"]},"author_link":["2308","27192","27193"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-03-16","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"137101","bibliographicVolumeNumber":"799","bibliographic_titles":[{"bibliographic_title":"Neuroscience Letters"},{"bibliographic_title":"Neuroscience Letters","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Various brain regions/nuclei project axons to the subventricular zone (SVZ), a postnatal neurogenic niche. In adults, neurogenesis is controlled by neuronal activity, via neurotransmitters. Glutamate is a major excitatory neurotransmitter, and glutamate receptors are expressed in SVZ cells. Although the cerebral cortex is a major source of glutamate and the medial cortex projects axons to the medial striatum next to the SVZ, it remains unclear whether cortical neurons regulate adult neurogenesis in vivo. First, to analyze axonal projection, plasmid vector expressing DsRed was introduced to the medial cortex by in utero electroporation. At the adult stage, DsRed-labeled axons were detected in the dorsolateral, striatal, and septal areas of the SVZ, and where they were in contact with neuroblasts. Furthermore, maturation of the cortical projection and the SVZ appeared to synchronize during postnatal stages. Next, stab injuries were made in the bilateral medial cortex to interrupt cortical input to the SVZ. At 17 days post-injury, cell proliferation in the SVZ and tangential migration of neuroblasts to the olfactory bulb were not significantly affected. There were clusters of neuroblasts in the striatum close to the SVZ in all experimental groups, but the number and size of neuroblast clusters were significantly larger in the medial cortex-injured group compared with the other experimental groups. These neuroblast clusters had a morphology of tangentially migrating cells to the olfactory bulb. These results suggest that cortical input to the SVZ inhibits the radial migration of neuroblasts to converge with the migration pathway in vivo.","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier"}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.neulet.2023.137101","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Neuroscience Letters. 799, 137101, doi:10.1016/j.neulet.2023.137101"}]}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://www.sciencedirect.com/science/article/pii/S0304394023000551"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.sciencedirect.com/science/article/pii/S0304394023000551","subitem_relation_type_select":"URI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"(C) 2023 Elsevier B.V."}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03043940","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_26":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_text_value":"18727972"}]},"item_10001_text_33":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Biological Regulation, School of Health Science, Faculty of Medicine, Tottori University"},{"subitem_text_language":"en","subitem_text_value":"Department of Biological Regulation, School of Health Science, Faculty of Medicine, Tottori University"},{"subitem_text_language":"en","subitem_text_value":"Department of Biological Regulation, School of Health Science, Faculty of Medicine, Tottori University"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"森, 徹自"},{"creatorName":"モリ, テツジ","creatorNameLang":"ja-Kana"},{"creatorName":"Mori, Tetsuji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2308","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"30285043","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=30285043"},{"nameIdentifier":"100001237","nameIdentifierScheme":"研究者総覧鳥取大学","nameIdentifierURI":"http://researchers.adm.tottori-u.ac.jp/html/100001237_ja.html"}]},{"creatorNames":[{"creatorName":"Ota, Rei","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"27192","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshida, Ryota","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"27193","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2024-04-01"}],"displaytype":"detail","filename":"nl799_137101.pdf","filesize":[{"value":"4.9 MB"}],"format":"application/pdf","licensefree":"(C) 2023 Elsevier B.V.","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"nl799_137101.pdf","url":"https://repository.lib.tottori-u.ac.jp/record/7316/files/nl799_137101.pdf"},"version_id":"7417d579-c59e-49cc-baa1-47a6e7a26f20"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Adult neurogenesis","subitem_subject_scheme":"Other"},{"subitem_subject":"Cortical projection","subitem_subject_scheme":"Other"},{"subitem_subject":"Cell migration","subitem_subject_scheme":"Other"},{"subitem_subject":"Injury","subitem_subject_scheme":"Other"},{"subitem_subject":"Subventricular zone","subitem_subject_scheme":"Other"},{"subitem_subject":"Adult neurogenesis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Cortical projection","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Cell migration","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Injury","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Subventricular zone","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Cortical projection to the subventricular zone and its effect on adult neurogenesis in mice","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Cortical projection to the subventricular zone and its effect on adult neurogenesis in mice","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"10","path":["12","9"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-02-10"},"publish_date":"2023-02-10","publish_status":"0","recid":"7316","relation_version_is_last":true,"title":["Cortical projection to the subventricular zone and its effect on adult neurogenesis in mice"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2023-11-22T01:50:55.997884+00:00"}