@article{oai:repository.lib.tottori-u.ac.jp:00007339,
 author = {大倉, 毅 and Okura, Tsuyoshi and 藤岡, 洋平 and Fujioka, Yohei and 角, 啓佑 and 松澤, 和彦 and Matsuzawa, Kazuhiko and 伊澤, 正一郎 and Izawa, Shoichiro and 上田, 悦子 and Ueta, Etsuko and 加藤, 雅彦 and Kato, Masahiko and 今村, 武史 and Imamura, Takeshi and 谷口, 晋一 and Taniguchi, Shin-ichi and 山本, 一博 and Yamamoto, Kazuhiro and Nakamura, Risa and Kawamoto-Kitao, Sonoko and Ito, Yuichi and Matsumoto, Kazuhisa and Shoji, Kyoko and Sumi, Keisuke},
 issue = {7},
 journal = {PLOS ONE, PLOS ONE},
 month = {Jul},
 note = {Background: Screening for undiagnosed type 2 diabetes mellitus is recommended for Asian Americans with a body mass index ≥23. However, the optimal body mass index cut-off score for predicting the risk of diabetes mellitus in Japanese people is not well known. The aim of this study was to determine the best body mass index cut-off score for predicting insulin resistance and diabetes mellitus in the Japanese population. Methods: This study had two parts, a clinical investigation and a retrospective observational investigation. In the clinical part of the study, 58 participants (26 with type 2 diabetes mellitus and 32 non-diabetics) underwent a hyperinsulinemic-euglycemic clamp from which their glucose disposal rate was measured. For the retrospective part of the study, medical check-up data from 88,305 people in the Tottori Prefecture were analyzed for clinical evidence of diabetes mellitus. The optimal BMI cut-off scores for prediction of insulin resistance and diabetes mellitus were determined. Results: In the clamp study, the optimal body mass index cut-off score to predict insulin resistance in non-diabetic patients was 22.7. All participants with type 2 diabetes mellitus were insulin resistant, and the optimal body mass index cut-off score for prediction of severe insulin resistance was 26.2. When the data from the type 2 diabetic and the non-diabetic participants were combined, the optimal body mass index cut-off score for prediction of insulin resistance was 23.5. Analysis of 88,305 medical check-up records yielded an optimal body mass index cut-off score for prediction of diabetes mellitus of 23.6. Conclusions: These results suggest that having a body mass index ≥23 is a risk factor for insulin resistance and diabetes mellitus in the Japanese population.},
 title = {Body mass index >= 23 is a risk factor for insulin resistance and diabetes in Japanese people: A brief report},
 volume = {13},
 year = {2018},
 yomi = {オオクラ, ツヨシ and フジオカ, ヨウヘイ and スミ, ケイスケ and マツザワ, カズヒコ and イザワ, ショウイチロウ and ウエタ, エツコ and カトウ, マサヒコ and イマムラ, タケシ and タニグチ, シンイチ and ヤマモト, カズヒロ and スミ, ケイスケ}
}