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カエル心筋におけるピクロトキシンの収縮抑制作用
https://repository.lib.tottori-u.ac.jp/records/1258
https://repository.lib.tottori-u.ac.jp/records/12589619d0e0-4395-4a73-ac3d-8eb9bb7d2620
| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2021-11-25 | |||||
| タイトル | ||||||
| タイトル | カエル心筋におけるピクロトキシンの収縮抑制作用 | |||||
| 言語 | ja | |||||
| タイトル | ||||||
| タイトル | Picrotoxin Inhibits Contractions in Frog Heart Atrium | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | Picrotoxin | |||||
| キーワード | ||||||
| 主題 | Contraction | |||||
| キーワード | ||||||
| 主題 | Heart muscle | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | Picrotoxin | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | Contraction | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | Heart muscle | |||||
| 資源タイプ | ||||||
| 資源タイプ | departmental bulletin paper | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| 著者 |
竹田, 公久
× 竹田, 公久× Guibert, Richard× Takeda, Kimihisa |
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| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Laboratoire de Physiologie Cellulaire Cardiaque, U-241, INSERM, Universite Paris-Sud, F-91405 Orsay, France | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Visitor from (and correspondence should be addressed to) Laboratory of Physiology, Faculty of Education, Tottori University | |||||
| 抄録 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Effects of 5mM picrotoxin on action potentials and contractions of frog heart muscle were examined by simultaneous recording of electrical and mechanical activity using double mannitol-gap method. With short time exposure, picrotoxin did not affect the action potential appreciably, but reduced the twitch tension to about one third. On return to Ringer solution, the reduction in the tension was almost fully recovered within several minutes. With long time exposure, picrotoxin considerably reduced the depolarization at the plateau phase of the action potential, and the twitch tension was reduced to below one tenth. These effects could not be recovered within relatively short time. The results reveal, for the first time, the effect of picrotoxin to inhibit contraction in heart muscle, in contrast to its potentiation of contraction in skeleton muscle. The long time effects of picrotoxin could be ascribed to the inhibition of Ca current with picrotoxin, but the short time effect of picrotoxin to inhibit contraction should be caused by other mechanism. | |||||
| 書誌情報 |
ja : 鳥取大学教育学部研究報告. 自然科学 en : The Journal of the Faculty of Education, Tottori University. Natural science 巻 44, 号 2, p. 131-136, 発行日 1995-12-28 |
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| 出版者 | ||||||
| 出版者 | 鳥取大学教育学部 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 03715965 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00174585 | |||||
| 権利 | ||||||
| 権利情報 | 注があるものを除き、この著作物は日本国著作権法により保護されています。 / This work is protected under Japanese Copyright Law unless otherwise noted. | |||||
| 情報源 | ||||||
| 関連名称 | 鳥取大学教育学部研究報告. 自然科学. 1995. 44(2), 131-136. | |||||
