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Predictors of Renal Replacement Therapy Requirement in Acute Kidney Injury Due to Urinary Sepsis: A Single-Center Retrospective Study
https://repository.lib.tottori-u.ac.jp/records/2001981
https://repository.lib.tottori-u.ac.jp/records/20019817a8c0f02-1f53-4618-a103-2eda911f14bd
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yam68(3)_220.pdf (766 KB)
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© 2025 Tottori University Medical Press
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| Item type | デフォルトアイテムタイプ（フル）(1) | |||||||||||||||
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| 公開日 | 2025-09-04 | |||||||||||||||
| タイトル | ||||||||||||||||
| タイトル | Predictors of Renal Replacement Therapy Requirement in Acute Kidney Injury Due to Urinary Sepsis: A Single-Center Retrospective Study | |||||||||||||||
| 言語 | en | |||||||||||||||
| 作成者 |
Yasukawa,Ryusei
× Yasukawa,Ryusei
× Sejima,Takehiro
× 岩本,秀人× 森實,修一
研究者総覧鳥取大学
100000269_ja.html
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| 主題 | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | acute kidney injury | |||||||||||||||
| 主題 | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | renal replacement therapy | |||||||||||||||
| 主題 | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | urosepsis | |||||||||||||||
| 内容記述 | ||||||||||||||||
| 内容記述タイプ | Other | |||||||||||||||
| 内容記述 | Background, Urosepsis is defined as sepsis caused by an infection of the urogenital tract and is a systemic response to infection. Urosepsis is commonly treated in the intensive care unit (ICU) because of its acute and potentially lethal nature. Acute kidney injury (AKI) is a common complication of septic shock in ICU patients. This study predicted cases in which patients required renal replacement therapy (RRT) during the early stages of hospitalization. We also examined the relationship between the clinical information obtained at admission and the subsequent need for RRT. Methods, This single-center, retrospective, observational study included 114 patients with sepsis caused by tract infections. We examined the multiple factors associated with AKI using clinical and social information. AKI was defined according to the Kidney Disease Improving Global Outcomes (KDIGO) Clinical Practice Guidelines, with severe AKI defined as AKI requiring RRT. Logistic regression analyses were performed to identify the significant factors associated with severe AKI based on the information obtained at the time of admission. Results, Severe AKI occurred in 12 patients. Multivariate analysis revealed that two factors were significantly associated with severe AKI: a high leukocyte count in the peripheral blood (> 22,100/μL) at admission (odds ratio: 21.972, 95% CI: 1.798–268.481) and the administration of vasopressors (odds ratio: 13.327, 95% CI: 1.009–176.091). Conclusion, Physicians should be vigilant of the potential development of severe AKI in cases of urosepsis, particularly when patients require vasopressor and present with extremely high peripheral blood leukocyte counts at admission. | |||||||||||||||
| 言語 | en | |||||||||||||||
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| 出版者 | Tottori University Medical Press | |||||||||||||||
| 言語 | en | |||||||||||||||
| 日付 | ||||||||||||||||
| 日付 | 2025-08-22 | |||||||||||||||
| 日付タイプ | Issued | |||||||||||||||
| 言語 | ||||||||||||||||
| 言語 | eng | |||||||||||||||
| 資源タイプ | ||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||
| 資源タイプ | journal article | |||||||||||||||
| 出版タイプ | ||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||
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| 関連タイプ | isIdenticalTo | |||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||
| 関連識別子 | https://doi.org/10.33160/yam.2025.08.010 | |||||||||||||||
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| 関連タイプ | isIdenticalTo | |||||||||||||||
| 識別子タイプ | URI | |||||||||||||||
| 関連識別子 | https://www.lib.tottori-u.ac.jp/yam/yam/yam68-3/68-3contents.html | |||||||||||||||
| 収録物識別子 | ||||||||||||||||
| 収録物識別子タイプ | EISSN | |||||||||||||||
| 収録物識別子 | 13468049 | |||||||||||||||
| 書誌情報 |
en : Yonago Acta Medica 巻 68, 号 3, p. 220-226, ページ数 7, 発行日 2025-08-22 |
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| 見出し | ||||||||||||||||
| 大見出し | Original Article | |||||||||||||||
| 言語 | en | |||||||||||||||
| 出版者情報 | ||||||||||||||||
| 出版者名 | Tottori University Medical Press | |||||||||||||||
| 言語 | en | |||||||||||||||
| アクセス権 | ||||||||||||||||
| アクセス権 | open access | |||||||||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||||||
| 権利情報 | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 権利情報 | © 2025 Tottori University Medical Press | |||||||||||||||
