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Thyroid hormone may predict treatment failure in Kawasaki disease

https://repository.lib.tottori-u.ac.jp/records/2002031
https://repository.lib.tottori-u.ac.jp/records/2002031
c59ad109-2152-4c20-abee-22c89ca3743d
名前 / ファイル ライセンス アクション
PediatrInt66(1)_e15723.pdf PediatrInt66(1)_e15723.pdf (958 KB)
This is the peer reviewed version of the following article: [Hashida Y, Mino Y, Okuno K, Uemasu H, Sakata S, Fujimoto M, et al. Thyroid hormone may predict treatment failure in Kawasaki disease. Pediatr Int. 2024; 66:e15723.], which has been published in final form at [https://doi.org/10.1111/ped.15723]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.
アイテムタイプ デフォルトアイテムタイプ(フル)(1)
公開日 2026-01-15
タイトル
タイトル Thyroid hormone may predict treatment failure in Kawasaki disease
言語 en
作成者 Hashida,Yuichiro

× Hashida,Yuichiro

en Hashida,Yuichiro(Personal)
Tottori University

ja kakenhi 鳥取大学 15101

Search repository
美野,陽一

× 美野,陽一

研究者総覧鳥取大学 100000263_ja.html

en Mino,Yoichi(Personal)
Tottori University

ja 美野,陽一(Personal)
kakenhi 鳥取大学 15101

Search repository
奥野,啓介

× 奥野,啓介

研究者総覧鳥取大学 100000861_ja.html
e-Rad_Researcher 10597959

en Okuno,Keisuke(Personal)
Tottori University

ja 奥野,啓介(Personal)
kakenhi 鳥取大学 15101

Search repository
上桝,仁志

× 上桝,仁志

研究者総覧鳥取大学 100002725_ja.html

en Uemasu,Hitoshi(Personal)
Tottori University

ja 上桝,仁志(Personal)
kakenhi 鳥取大学 15101

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Sakata,Shinji

× Sakata,Shinji

en Sakata,Shinji(Personal)
Tottori University

ja kakenhi 鳥取大学 15101

Search repository
藤本,正伸

× 藤本,正伸

研究者総覧鳥取大学 100001495_ja.html
e-Rad_Researcher 80745224

en Fujimoto,Masanobu(Personal)
Tottori University

ja 藤本,正伸(Personal)
kakenhi 鳥取大学 15101

Search repository
難波,範行

× 難波,範行

研究者総覧鳥取大学 100002101_ja.html
e-Rad_Researcher 10379076

en Namba,Noriyuki(Personal)
Tottori University

ja 難波,範行(Personal)
kakenhi 鳥取大学 15101

Search repository
主題
言語 en
主題Scheme Other
主題 Intravenous immunoglobulin
主題
言語 en
主題Scheme Other
主題 Kawasaki disease
主題
言語 en
主題Scheme Other
主題 thyroid-stimulating hormone
主題
言語 en
主題Scheme Other
主題 thyroxine
主題
言語 en
主題Scheme Other
主題 triiodothyronine
内容記述
内容記述タイプ Other
内容記述 Background, In systemic inflammatory conditions, inflammatory cytokines can cause low thyroid hormone levels. There are no reports discussing the relation between thyroid hormone levels and response to treatment for Kawasaki disease. Methods, We investigated 67 patients who underwent treatment in the acute phase of Kawasaki disease. We divided patients into two groups based on their response to initial intravenous immunoglobulin (IVIG) treatment: the responder group (n=40), and the non-responder group (n=27). The serum levels of the thyroid hormones free triiodothyronine (FT3), free thyroxine (FT4), and thyroid-stimulating hormone (TSH) were compared before and after treatment in all patients, and between responder and non-responder groups. Results, FT3, FT4, and TSH levels were low before the initial treatment and increased significantly after treatment (p<0.05). FT3, FT4, and TSH levels before treatment were significantly lower in the non-responder group than in the responder group (p<0.05). Logistic regression analysis implied that adding FT4 to the Gunma score improved the accuracy of treatment failure. Conclusions, Thyroid hormone and TSH levels were lower in the non-responder group than in the responder group in the initial IVIG treatment for Kawasaki disease. This study suggests that Kawasaki disease in the acute phase is associated with low thyroid hormone levels and TSH. It is possible that these hormone levels predict response to the initial IVIG.
言語 en
出版者
出版者 John Wiley & Sons
言語 en
日付
日付 2024-02-07
日付タイプ Issued
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
関連情報
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1111/ped.15723
収録物識別子
収録物識別子タイプ EISSN
収録物識別子 1442200X
収録物識別子
収録物識別子タイプ PISSN
収録物識別子 13288067
書誌情報 en : Pediatrics International

巻 66, 号 1, p. e15723, 発行日 2024-02-07
出版者情報
出版者名 John Wiley & Sons
言語 en
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
権利情報 © 2024 Japan Pediatric Society.
言語 en
権利情報
権利情報 This is the peer reviewed version of the following article: [Hashida Y, Mino Y, Okuno K, Uemasu H, Sakata S, Fujimoto M, et al. Thyroid hormone may predict treatment failure in Kawasaki disease. Pediatr Int. 2024; 66:e15723.], which has been published in final form at [https://doi.org/10.1111/ped.15723]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.
言語 en
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