{"_buckets": {"deposit": "38db2344-242e-4e78-9342-ddaeb9bc8b85"}, "_deposit": {"created_by": 1, "id": "4614", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "4614"}, "status": "published"}, "_oai": {"id": "oai:repository.lib.tottori-u.ac.jp:00004614", "sets": ["9", "12", "976"]}, "author_link": ["16508", "16506", "3159", "4943", "16507", "16512", "16510", "16511", "16509"], "item_10001_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2023-02-20", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "111", "bibliographicPageStart": "104", "bibliographicVolumeNumber": "66", "bibliographic_titles": [{"bibliographic_title": "Yonago Acta Medica"}, {"bibliographic_title": "Yonago Acta Medica", "bibliographic_titleLang": "en"}]}]}, "item_10001_checkbox_27": {"attribute_name": "部局名", "attribute_value_mlt": [{"subitem_checkbox_item": ["i-gakubu"]}]}, "item_10001_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Background: Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli has been increasingly recognized as the cause of upper urinary tract infection (UTI) in children. We have been using flomoxef at our department since 2017 as the first-line empiric therapy for children diagnosed with UTIs, and we avoid using carbapenems, which are considered the first-line treatment for ESBL-producing E. coli. However, reports on the use of flomoxef for UTIs are limited, especially for pediatric patients. The presence of vesicoureteral reflux at the onset of pyelonephritis is a concern. Severe vesicoureteral reflux can lead to repeated UTI and future deterioration of renal function, but the indication for voiding urethrography, which closely examines the presence of vesicoureteral reflux complications, is controversial. Methods: We retrospectively reviewed the laboratory findings, treatment, and clinical course of 96 pyelonephritis cases experienced at our department over a 7-year period from April 2014 to March 2021. Results: ESBL-producing E. coli were identified as the cause of pyelonephritis in 51% of cases, and this value was significantly higher (88%) in 2017. No significant differences were found in the febrile period or recurrence rate between the flomoxef-initiated group and other antibiotics groups. We also examined clinical indicators to predict vesicoureteral reflux and found no significant differences in ultrasonographic findings of hydronephrosis. Conclusion: In the present series, 51% of all pyelonephritis cases were found to be caused by ESBL-producing E. coli, with a significant increase in recent years. Flomoxef may be a useful alternative to carbapenem for ESBL-producing E. coli and the initial antibiotic of choice for upper UTIs in children. The indication for voiding cystourethrography should be carefully determined.", "subitem_description_type": "Abstract"}]}, "item_10001_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Tottori University Medical Press"}]}, "item_10001_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.33160/yam.2023.02.013", "subitem_relation_type_select": "DOI"}}]}, "item_10001_relation_16": {"attribute_name": "情報源", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "Yonago Acta Medica. 2023, 66(1), 104-111. doi:10.33160/yam.2023.02.013"}]}]}, "item_10001_relation_17": {"attribute_name": "関連サイト", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "https://www.lib.tottori-u.ac.jp/yam/yam/yam66-1/66-1contents.html"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": 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"EISSN", "attribute_value_mlt": [{"subitem_text_value": "13468049"}]}, "item_10001_text_29": {"attribute_name": "最新掲載誌名", "attribute_value_mlt": [{"subitem_text_value": "yam;Yonago Acta medica;Yonago Acta medica"}]}, "item_10001_text_33": {"attribute_name": "著者所属（英）", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "Department of Pediatrics, Matsue City Hospital"}, {"subitem_text_language": "en", "subitem_text_value": "Department of Pediatrics, Matsue City Hospital / Division of Pediatrics and Perinatology, Department of Multidisciplinary Internal Medicine, School of Medicine, Faculty of Medicine, Tottori University"}, {"subitem_text_language": "en", "subitem_text_value": "Department of Pediatrics, Matsue City Hospital"}, {"subitem_text_language": "en", "subitem_text_value": "Department of Pediatrics, Matsue City Hospital"}, {"subitem_text_language": "en", "subitem_text_value": "Department of Pediatrics, Matsue City Hospital"}, {"subitem_text_language": "en", "subitem_text_value": "Department of Pediatrics, Matsue City Hospital"}, {"subitem_text_language": "en", "subitem_text_value": "Division of Pediatrics and Perinatology, Department of Multidisciplinary Internal Medicine, School of Medicine, Faculty of Medicine, Tottori University"}, {"subitem_text_language": "en", "subitem_text_value": "Department of Pediatrics, Matsue City Hospital"}]}, "item_10001_version_type_20": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "佐野, 仁志"}, {"creatorName": "サノ, ヒトシ", "creatorNameLang": "ja-Kana"}, {"creatorName": "Sano, Hitoshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "3159", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "100001310", "nameIdentifierScheme": "研究者総覧鳥取大学", 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"subitem_subject_scheme": "Other"}, {"subitem_subject": "urinary tract infections", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "vesico-ureteral reflux", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Cases of Pediatric Pyelonephritis: A Single-Center Retrospective Study from an Extended-Spectrum β-Lactamase-Producing Escherichia coli Endemic Area in Japan", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Cases of Pediatric Pyelonephritis: A Single-Center Retrospective Study from an Extended-Spectrum β-Lactamase-Producing Escherichia coli Endemic Area in Japan", "subitem_title_language": "en"}]}, "item_type_id": "10001", "owner": "1", "path": ["9", "12", "976"], "permalink_uri": "https://repository.lib.tottori-u.ac.jp/records/4614", "pubdate": {"attribute_name": "公開日", "attribute_value": "2023-02-28"}, "publish_date": "2023-02-28", "publish_status": "0", "recid": "4614", "relation": {}, "relation_version_is_last": true, "title": ["Cases of Pediatric Pyelonephritis: A Single-Center Retrospective Study from an Extended-Spectrum β-Lactamase-Producing Escherichia coli Endemic Area in Japan"], "weko_shared_id": -1}