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  1. 学部学科区分一覧
  2. 医学部・医学系研究科・医学部附属病院
  1. 資料タイプ一覧
  2. 学術雑誌論文
  1. 鳥取大学の刊行物
  2. Yonago Acta Medica
  3. 65
  4. 3

Comprehensive Investigations of Multiple Factors That Are Related to Refractory Outcome in Urosepsis Patients

https://repository.lib.tottori-u.ac.jp/records/4655
https://repository.lib.tottori-u.ac.jp/records/4655
e4aa495e-48ea-4176-8579-c9b14852f876
名前 / ファイル ライセンス アクション
yam65(3)_254.pdf yam65(3)_254.pdf (627.9 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2022-09-07
タイトル
タイトル Comprehensive Investigations of Multiple Factors That Are Related to Refractory Outcome in Urosepsis Patients
言語 en
言語
言語 eng
キーワード
主題 sepsis
キーワード
主題 urinary tract infection
キーワード
主題 urosepsis
キーワード
言語 en
主題 sepsis
キーワード
言語 en
主題 urinary tract infection
キーワード
言語 en
主題 urosepsis
資源タイプ
資源タイプ journal article
著者 Sejima, Takehiro

× Sejima, Takehiro

WEKO 16643

Sejima, Takehiro

ja-Kana セジマ, タケヒロ

Search repository
眞砂, 俊彦

× 眞砂, 俊彦

WEKO 16644

眞砂, 俊彦

ja-Kana マサゴ, トシヒコ

Search repository
森實, 修一

× 森實, 修一

WEKO 2322
e-Rad 50419496
研究者総覧鳥取大学 100000269

森實, 修一

ja-Kana モリザネ, シュウイチ

en Morizane, Shuichi

Search repository
本田, 正史

× 本田, 正史

WEKO 775
e-Rad 20362890
研究者総覧鳥取大学 100000422

本田, 正史

ja-Kana ホンダ, マサシ

en Honda, Masashi

Search repository
武中, 篤

× 武中, 篤

WEKO 3662
e-Rad 50368669
研究者総覧鳥取大学 100000180

武中, 篤

ja-Kana タケナカ, アツシ

en Takenaka, Atsushi

Search repository
Sejima, Takehiro

× Sejima, Takehiro

WEKO 16645

en Sejima, Takehiro

ja-Kana セジマ, タケヒロ

Search repository
Masago, Toshihiko

× Masago, Toshihiko

WEKO 16646

en Masago, Toshihiko

ja-Kana マサゴ, トシヒコ

Search repository
著者所属(英)
言語 en
値 Department of Urology, Matsue-city Hospital
著者所属(英)
言語 en
値 Department of Urology, Matsue-city Hospital
著者所属(英)
言語 en
値 Division of Urology, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University
著者所属(英)
言語 en
値 Division of Urology, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University
著者所属(英)
言語 en
値 Division of Urology, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University
抄録
内容記述タイプ Other
内容記述 Background: Urosepsis is an acute life-threating disease, and some cases show refractory outcome to therapy. In an aging society of developed countries, characteristics of urosepsis are becoming complicated. We performed a comprehensive investigation regarding the clinical and social aspects that are related to refractory outcomes in urosepsis patients. Methods: The patient cohort consisted of 66 patients with urosepsis. Multiple factors from clinical and social aspects were reviewed retrospectively. Two categories of refractory outcomes were defined. One was afebrile resistance (AR); fever continued more than 7 days from the initiation of therapy. Another was discharge resistance (DR); hospitalization continued for more than 30 days. Logistic regression analyses were performed to identify significant factors that are related to the AR or DR. Results: Univariate analysis demonstrated that high score of Eastern Cooperative Oncology Group Performance Status (ECOG PS) (? 2) and Age-adjusted Charlson comorbidity index (CCI) (? 4), high serum C-reactive protein (CRP) level (? 14.9 mg/dL), and low serum albumin level (? 2.26 g/dL) were significantly related to AR. Univariate analysis results also revealed that high score of ECOG PS (? 2), high serum creatinine level (? 1.54 mg/dL) and vasopressor administration were significantly related to DR. Multivariate analyses demonstrated that low serum albumin level (? 2.26g/dL) was the only significant factor that was related to AR. In contrast, high score of ECOG PS (? 2) and high serum creatinine level (? 1.54 mg/dL) were significant factors that were related to DR. Conclusion: It is suggested that evaluating serum albumin levels is essential for the therapeutic first step because hypoalbuminemia was the significant factor that was related to obstruction to antipyresis. It is also suggested that the deterioration of patients’ activities of daily living and renal dysfunction might be the refractory factors for discharge from the hospital, which was the ultimate therapeutic goal.
書誌情報 Yonago Acta Medica
en : Yonago Acta Medica

巻 65, 号 3, p. 254-261, 発行日 2022-08-29
出版者
出版者 Tottori University Medical Press
ISSN
収録物識別子タイプ ISSN
収録物識別子 05135710
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00892882
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 10.33160/yam.2022.08.012
権利
権利情報 (C) 2022 Tottori University Medical Press.
情報源
関連名称 Yonago Acta Medica. 2022, 65(3), 254-261. doi:10.33160/yam.2022.08.012
関連サイト
識別子タイプ URI
関連識別子 https://www.lib.tottori-u.ac.jp/yam/yam/yam65-3/65-3contents.html
関連名称 https://www.lib.tottori-u.ac.jp/yam/yam/yam65-3/65-3contents.html
関連サイト
識別子タイプ DOI
関連識別子 https://doi.org/10.33160/yam.2022.08.012
関連名称 https://doi.org/10.33160/yam.2022.08.012
著者版フラグ
出版タイプ VoR
EISSN
値 13468049
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