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Marathoners’ Breathing Pattern Protects Against Lung Injury by Mechanical Ventilation: An Ex Vivo Study Using Rabbit Lungs
https://repository.lib.tottori-u.ac.jp/records/4747
https://repository.lib.tottori-u.ac.jp/records/47475209b5f4-4449-4753-9a72-9002ff6e9bbc
| 名前 / ファイル | ライセンス | アクション |
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yam63(4)_272.pdf (1.2 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2020-12-04 | |||||
| タイトル | ||||||
| タイトル | Marathoners’ Breathing Pattern Protects Against Lung Injury by Mechanical Ventilation: An Ex Vivo Study Using Rabbit Lungs | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | 2:2 breathing rhythm | |||||
| キーワード | ||||||
| 主題 | lung-protective ventilation strategy | |||||
| キーワード | ||||||
| 主題 | marathon | |||||
| キーワード | ||||||
| 主題 | perfused lung | |||||
| キーワード | ||||||
| 主題 | ventilator-induced lung injury | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | 2:2 breathing rhythm | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | lung-protective ventilation strategy | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | marathon | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | perfused lung | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | ventilator-induced lung injury | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
オカザキ, ナオト
× オカザキ, ナオト× 舩木, 一美× 大槻, 明広× 高橋, 俊作× 原田, 知実× 稲垣, 喜三× Oshima, Yoshiaki× Okazaki, Naoto× Takahashi, Shunsaku |
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| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Division of Anesthesiology and Critical Care Medicine, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University / Department of Anesthesiology, Yonago Medical Center | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Division of Anesthesiology and Critical Care Medicine, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Division of Anesthesiology and Critical Care Medicine, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Division of Anesthesiology and Critical Care Medicine, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Division of Anesthesiology and Critical Care Medicine, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University / Department of Anesthesiology, Tottori Prefectural Central Hospital | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Division of Anesthesiology and Critical Care Medicine, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University / Department of Anesthesiology, Ehime Prefectural Central Hospital | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Division of Anesthesiology and Critical Care Medicine, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University | |||||
| 抄録 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | [Background] Breathing during a marathon is often empirically conducted in a so-called “2:2 breathing rhythm,” which is based on a four-phase cycle, consisting of the 1st and 2nd inspiratory and the 1st and 2nd expiratory phases. We developed a prototype ventilator that can perform intermittent positive pressure ventilation, mimicking the breathing cycle of the 2:2 breathing rhythm. This mode of ventilation was named the marathoners’ breathing rhythm ventilation (MBV). We hypothesized that MBV may have a lung protective effect. [Methods] We examined the effects of the MBV on the pulmonary pre-edema model in isolated perfused rabbit lungs. The pulmonary pre-edema state was induced using bloodless perfusate with low colloid osmotic pressure. The 14 isolated rabbit lung preparations were randomly divided into the conventional mechanical ventilation (CMV) group and MBV group, (both had an inspiratory/expiratory ratio of 1/1). In the CMV group, seven rabbit lungs were ventilated using the Harvard Ventilator 683 with a tidal volume (TV) of 8 mL/kg, a respiratory rate (RR) of 30 cycles/min, and a positive end-expiratory pressure (PEEP) of 2 cmH2O for 60 min. In the MBV group, seven rabbit lungs were ventilated using the prototype ventilator with a TV of 6 mL/kg, an RR of 30 cycles/min, and a PEEP of 4 cmH2O (first step) and 2 cmH2O (second step) for 60 min. The time allocation of the MBV for one cycle was 0.3 s for each of the 1st and 2nd inspiratory and expiratory phases with 0.2 s of intermittent resting between each phase. [Results] Peak airway pressure and lung wet-to-dry ratio after 60 min of ventilation were lower in the MBV group than in the CMV group. [Conclusion] MBV was considered to have a lung-protective effect compared to CMV. | |||||
| 書誌情報 |
Yonago Acta Medica en : Yonago Acta Medica 巻 63, 号 4, p. 272-281, 発行日 2020-11-24 |
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| 雑誌内区分 | ||||||
| 値 | Original Articles | |||||
| 出版者 | ||||||
| 出版者 | Tottori University Medical Press | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 05135710 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00892882 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.33160/yam.2020.11.005 | |||||
| 権利 | ||||||
| 権利情報 | Yonago Acta medica 編集委員会 | |||||
| 情報源 | ||||||
| 関連名称 | Oshima Yoshiaki, Okazaki Naoto, Funaki Kazumi, et al. Marathoners’ Breathing Pattern Protects Against Lung Injury by Mechanical Ventilation: An Ex Vivo Study Using Rabbit Lungs. 2020, 63(4). 272-281. doi:10.33160/yam.2020.11.005 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.jstage.jst.go.jp/article/yam/63/4/63_2020.11.005/_article/ | |||||
| 関連名称 | https://www.jstage.jst.go.jp/article/yam/63/4/63_2020.11.005/_article/ | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.lib.tottori-u.ac.jp/yam/yam/yam63-4/63-4contents.html | |||||
| 関連名称 | http://www.lib.tottori-u.ac.jp/yam/yam/yam63-4/63-4contents.html | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| EISSN | ||||||
| 値 | 1346-8049 | |||||
