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Utility and Limitation of Preoperative Neutrophil Lymphocyte Ratio as a Prognostic Factor in Hepatocellular Carcinoma
https://repository.lib.tottori-u.ac.jp/records/4835
https://repository.lib.tottori-u.ac.jp/records/48354aa516de-b87d-4905-9a37-f22355f2d3c2
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
yam61(4)_197.pdf (928.9 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
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| 公開日 | 2019-01-09 | |||||||||
| タイトル | ||||||||||
| タイトル | Utility and Limitation of Preoperative Neutrophil Lymphocyte Ratio as a Prognostic Factor in Hepatocellular Carcinoma | |||||||||
| 言語 | en | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| キーワード | ||||||||||
| 主題 | hepatocellular carcinoma | |||||||||
| キーワード | ||||||||||
| 主題 | liver resection | |||||||||
| キーワード | ||||||||||
| 主題 | neutrophil-lymphocyte ratio | |||||||||
| キーワード | ||||||||||
| 主題 | prognostic factor | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題 | hepatocellular carcinoma | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題 | liver resection | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題 | neutrophil-lymphocyte ratio | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題 | prognostic factor | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ | journal article | |||||||||
| 著者 |
Uchinaka, Ei
× Uchinaka, Ei× Amisaki, Masataka× Morimoto, Masaki× Tokuyasu, Naruo× Sakamoto, Teruhisa× Honjo, Soichiro× Saito, Hiroaki× Fujiwara, Yoshiyuki
WEKO
377
× Uchinaka, Ei |
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| 著者所属 | ||||||||||
| 値 | Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||||||
| 著者所属 | ||||||||||
| 値 | Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||||||
| 著者所属 | ||||||||||
| 値 | Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||||||
| 著者所属 | ||||||||||
| 値 | Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||||||
| 著者所属 | ||||||||||
| 値 | Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||||||
| 著者所属 | ||||||||||
| 値 | Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||||||
| 著者所属 | ||||||||||
| 値 | Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||||||
| 著者所属 | ||||||||||
| 値 | Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||||||
| 著者所属（英） | ||||||||||
| 言語 | en | |||||||||
| 値 | Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||||||
| 著者所属（英） | ||||||||||
| 言語 | en | |||||||||
| 値 | Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||||||
| 著者所属（英） | ||||||||||
| 言語 | en | |||||||||
| 値 | Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||||||
| 著者所属（英） | ||||||||||
| 言語 | en | |||||||||
| 値 | Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||||||
| 著者所属（英） | ||||||||||
| 言語 | en | |||||||||
| 値 | Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||||||
| 著者所属（英） | ||||||||||
| 言語 | en | |||||||||
| 値 | Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||||||
| 著者所属（英） | ||||||||||
| 言語 | en | |||||||||
| 値 | Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||||||
| 著者所属（英） | ||||||||||
| 言語 | en | |||||||||
| 値 | Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||||||
| 抄録 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | 【Background】 The neutrophil lymphocyte ratio (NLR) has been proposed to be a surrogate marker of inflammation and immunological status and to have prognostic value in various malignancies. This study was conducted to clarify the prognostic significance of preoperative NLR in hepatocellular carcinoma (HCC). 【Methods】 We enrolled 135 patients with histologicallyproven HCC who underwent initial curative hepatectomy. Based on the median NLR values, patients were divided into: NLR ? 2.0 (NLR-high, n = 69) and NLR < 2.0 (NLR-low, n = 66). 【Results】 In univariate analysis, the 5-year overall survival (OS) rates were 59.8 % ± 6.7% and 75.6% ± 6.5% (P = 0.028) in the NLR-high and NLR-low groups, respectively. Furthermore, the 5-year disease specific survival rates were 68.6% ± 6.7%, and 81.2 ± 6.4% (P = 0.048) in the NLR-high and NLR-low groups, respectively. 【Conclusion】 Our results showed that high NLR was an independent predictor for OS in hepatectomy-treated HCC, suggesting that NLR may be a novel prognostic biomarker for HCC. On the other hand, NLR also has a limitation to predict postoperative prognosis of HCC patients by itself. | |||||||||
| 書誌情報 |
Yonago Acta Medica en : Yonago Acta Medica 巻 61, 号 4, p. 197-203, 発行日 2018-12-27 |
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| 出版者 | ||||||||||
| 出版者 | Tottori University Faculty of Medicine | |||||||||
| ISSN | ||||||||||
| 収録物識別子タイプ | ISSN | |||||||||
| 収録物識別子 | 05135710 | |||||||||
| 書誌レコードID | ||||||||||
| 収録物識別子タイプ | NCID | |||||||||
| 収録物識別子 | AA00892882 | |||||||||
| DOI | ||||||||||
| 関連タイプ | isIdenticalTo | |||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | 10.33160/yam.2018.12.002 | |||||||||
| 権利 | ||||||||||
| 権利情報 | Yonago Acta medica 編集委員会 | |||||||||
| 情報源 | ||||||||||
| 関連名称 | Yonago Acta Medica. 2018, 61(4),197-203 | |||||||||
| 関連サイト | ||||||||||
| 識別子タイプ | URI | |||||||||
| 関連識別子 | http://www.lib.tottori-u.ac.jp/yam/yam/yam61-4/61-4contents.html | |||||||||
| 関連名称 | http://www.lib.tottori-u.ac.jp/yam/yam/yam61-4/61-4contents.html | |||||||||
| 著者版フラグ | ||||||||||
| 出版タイプ | VoR | |||||||||
| EISSN | ||||||||||
| 値 | 1346-8049 | |||||||||
