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  1. 学部学科区分一覧
  2. 医学部・医学系研究科・医学部附属病院
  1. 資料タイプ一覧
  2. 学術雑誌論文
  1. 鳥取大学の刊行物
  2. Yonago Acta Medica
  3. 60
  4. 3

A Histopathologic Study of the Human Skin in the Early Stage After a Tick Bite: A Special Reference to Cutaneous Tissue Reaction to the Cement Substance of Tick Saliva

https://repository.lib.tottori-u.ac.jp/records/4870
https://repository.lib.tottori-u.ac.jp/records/4870
7a6d5e69-2796-4b03-b0f3-dae9da1959e6
名前 / ファイル ライセンス アクション
yam60(3)_186.pdf yam60(3)_186.pdf (8.8 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2018-06-22
タイトル
言語 en
タイトル A Histopathologic Study of the Human Skin in the Early Stage After a Tick Bite: A Special Reference to Cutaneous Tissue Reaction to the Cement Substance of Tick Saliva
言語
言語 eng
キーワード
主題 cement substance
キーワード
主題 cutaneous inflammatory reaction
キーワード
主題 histopathology
キーワード
主題 tick bite
キーワード
主題 tick saliva
キーワード
言語 en
主題 cement substance
キーワード
言語 en
主題 cutaneous inflammatory reaction
キーワード
言語 en
主題 histopathology
キーワード
言語 en
主題 tick bite
キーワード
言語 en
主題 tick saliva
資源タイプ
資源タイプ journal article
著者 Mihara, Motoyuki

× Mihara, Motoyuki

WEKO 17592

Mihara, Motoyuki

Search repository
Mihara, Motoyuki

× Mihara, Motoyuki

WEKO 17593

en Mihara, Motoyuki

Search repository
著者所属
Mihara Dermatology Clinic, Tottori University
抄録
内容記述タイプ Other
内容記述 The Ixodidae family of hard ticks has cement-producing and non-cement-producing species. Involved skins of four patients bitten by cement-producing ticks and two by non-cement-producing ticks were histopathologically examined. Those of the latter two patients were also studied immunohistochemically to characterize the infiltrating inflammatory cells. In patients with cement-producing ticks, the cement substance was observed as external cement or outer zone of internal cement, respectively. Coagulative necrosis was present in the epidermis in one patient and from the epidermis to the dermis in another patient. Epidermal cells were damaged in the remaining two patients. Despite these severe tissue damages, the cutaneous inflammatory reaction in all four patients was very mild. In contrast, the patients bitten by non-cement-producing ticks had severe cutaneous inflammatory reaction. In addition to caseous necrosis-like change in the entrance site of the inserted mouthparts, extensive interstitial lymphohistiocytic infiltrate was present diffusely from the dermis to the subcutaneous tissue. In one of the patients coagulative necrosis was present from the dermis to the subcutaneous tissue. Immunohistochemically, the infiltrating lymphocytes were T-cell dominant and mixed moderately with B-cells. Pathogenetically, the cutaneous inflammatory reaction is only mild in the skins involved by the cement-producing ticks, perhaps because inflammatory reaction in the host skin is suppressed by antiinflammatory and immunosuppressive substances contained in tick’s saliva in order to prevent position of their mouthparts fixed to the host skin from rejection of the host until finishing their engorgement. In contrast, the cutaneous inflammatory reaction induced by the non-cement-producing ticks is severe, possibly because these ticks have no antiinflammatory and immunosuppressive substances in their saliva, and because their saliva is much more injurious than that of the cement-producing ticks.
書誌情報 Yonago Acta Medica
en : Yonago Acta Medica

巻 60, 号 3, p. 186-199, 発行日 2017-09-15
出版者
出版者 Tottori University Faculty of Medicine
ISSN
収録物識別子タイプ ISSN
収録物識別子 05135710
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00892882
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 10.33160/yam.2017.09.009
権利
権利情報 Yonago Acta medica 編集委員会
情報源
関連名称 Yonago Acta Medica. 2017, 60(3), 186-199
関連サイト
識別子タイプ URI
関連識別子 http://www.lib.tottori-u.ac.jp/yam/yam/yam60-3/yam-60-186.pdf
関連名称 http://www.lib.tottori-u.ac.jp/yam/yam/yam60-3/yam-60-186.pdf
著者版フラグ
出版タイプ VoR
EISSN
1346-8049
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