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  1. 学部学科区分一覧
  2. 医学部・医学系研究科・医学部附属病院
  1. 資料タイプ一覧
  2. 学術雑誌論文
  1. 鳥取大学の刊行物
  2. Yonago Acta Medica
  3. 60
  4. 4

Prognostic Factors for Post Recurrence Survival in Resected Pathological Stage I Non-small Cell Lung Cancer

https://repository.lib.tottori-u.ac.jp/records/4874
https://repository.lib.tottori-u.ac.jp/records/4874
3250ceaf-2f68-4a8b-ad41-59585d0fd6e7
名前 / ファイル ライセンス アクション
yam60(4)_213.pdf yam60(4)_213.pdf (624.1 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2018-06-22
タイトル
言語 en
タイトル Prognostic Factors for Post Recurrence Survival in Resected Pathological Stage I Non-small Cell Lung Cancer
言語
言語 eng
キーワード
主題 epidermal growth factor receptor tyrosine kinase inhibitors
キーワード
主題 non-small cell lung cancer
キーワード
主題 post recurrecurrence
キーワード
主題 prognostic factor
キーワード
言語 en
主題 epidermal growth factor receptor tyrosine kinase inhibitors
キーワード
言語 en
主題 non-small cell lung cancer
キーワード
言語 en
主題 post recurrecurrence
キーワード
言語 en
主題 prognostic factor
資源タイプ
資源タイプ journal article
著者 Kubouchi, Yasuaki

× Kubouchi, Yasuaki

WEKO 17626

Kubouchi, Yasuaki

Search repository
Kidokoro, Yoshiteru

× Kidokoro, Yoshiteru

WEKO 1480
研究者総覧鳥取大学 100001254

Kidokoro, Yoshiteru

en Kidokoro, Yoshiteru

Search repository
Ohno, Takashi

× Ohno, Takashi

WEKO 17627

Ohno, Takashi

Search repository
Yurugi, Yohei

× Yurugi, Yohei

WEKO 17628

Yurugi, Yohei

Search repository
Wakahara, Makoto

× Wakahara, Makoto

WEKO 4126
研究者総覧鳥取大学 100001494

Wakahara, Makoto

en Wakahara, Makoto

Search repository
Haruki, Tomohiro

× Haruki, Tomohiro

WEKO 589
e-Rad 20529416
研究者総覧鳥取大学 100001147

Haruki, Tomohiro

en Haruki, Tomohiro

Search repository
Nakamura, Hiroshige

× Nakamura, Hiroshige

WEKO 2488
e-Rad 30252852
研究者総覧鳥取大学 100000400

Nakamura, Hiroshige

en Nakamura, Hiroshige

Search repository
Kubouchi, Yasuaki

× Kubouchi, Yasuaki

WEKO 17629

en Kubouchi, Yasuaki

Search repository
Ohno, Takashi

× Ohno, Takashi

WEKO 17630

en Ohno, Takashi

Search repository
Yurugi, Yohei

× Yurugi, Yohei

WEKO 17631

en Yurugi, Yohei

Search repository
著者所属
Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine
著者所属
Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine
著者所属
Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine
著者所属
Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine
著者所属
Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine
著者所属
Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine
著者所属
Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine
著者所属(英)
en
Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine
著者所属(英)
en
Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine
著者所属(英)
en
Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine
著者所属(英)
en
Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine
著者所属(英)
en
Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine
著者所属(英)
en
Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine
著者所属(英)
en
Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine
抄録
内容記述タイプ Other
内容記述 [Background]Recurrence of lung cancer after surgical resection is a major obstacle in the cure and long-term survival of patients and has become the most common cause of death. However, prognostic factors and efficacy of therapy after recurrence remain controversial. We evaluated the prognostic factors of post recurrence survival (PRS) in patients of resected stage I non-small cell lung cancer (NSCLC). [Methods]Of the 551 patients who underwent surgery for stage I NSCLC between 2005 and 2013, we reviewed 89 (16.2%) patients who had recurrence. We examined PRS using the Kaplan?Meier method and multivariate Cox regression analyses. [Results]The median follow-up period after recurrence was 21.0 months. The median recurrence free interval (RFI) was 16.8 months. The 1-year PRS and 3-year PRS were 65.6% and 44.7%, respectively. Multivariate analysis revealed that size of primary lesion > 25 mm (P = 0.048), RFI ? 17 months (P = 0.048) and no treatment for recurrence (P < 0.001) were independent poor-prognosis factors of PRS. We further examined PRS in 66 patients who underwent any post recurrence therapy. For the patients who underwent treatment after recurrence, bone metastasis (P = 0.025) and treatment without epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) (P = 0.049) were independent poor prognostic factors. [Conclusion]PRS may be associated with characteristics of a recurrent lesion, including the biology of the recurrent tumor, RFI, recurrent site, the treatment for recurrence, rather than characteristics of primary lesion. Although further validation is needed, this information is important for the design of clinical trials for post-recurrence therapy.
書誌情報 Yonago Acta Medica
en : Yonago Acta Medica

巻 60, 号 4, p. 213-219, 発行日 2018-02-05
出版者
出版者 Tottori University Faculty of Medicine
ISSN
収録物識別子タイプ ISSN
収録物識別子 05135710
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00892882
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 10.33160/yam.2017.12.001
権利
権利情報 Yonago Acta medica 編集委員会
情報源
関連名称 Yonago Acta Medica. 2017,60(4),213-219
関連サイト
識別子タイプ URI
関連識別子 http://www.lib.tottori-u.ac.jp/yam/yam/yam60-4/60-4contents.html
関連名称 http://www.lib.tottori-u.ac.jp/yam/yam/yam60-4/60-4contents.html
著者版フラグ
出版タイプ VoR
EISSN
1346-8049
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