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Circular Dichroism Studies on C-terminal Zinc Finger Domain of Transcription Factor GATA-2
https://repository.lib.tottori-u.ac.jp/records/5010
https://repository.lib.tottori-u.ac.jp/records/5010abd4aab7-c849-4b62-9802-886ce5ebae1c
名前 / ファイル | ライセンス | アクション |
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53_025-028.pdf (145.1 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2018-06-22 | |||||
タイトル | ||||||
タイトル | Circular Dichroism Studies on C-terminal Zinc Finger Domain of Transcription Factor GATA-2 | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題 | circular dichroism | |||||
キーワード | ||||||
主題 | GATA-2 | |||||
キーワード | ||||||
主題 | transcription factor | |||||
キーワード | ||||||
主題 | Zn finger | |||||
キーワード | ||||||
言語 | en | |||||
主題 | circular dichroism | |||||
キーワード | ||||||
言語 | en | |||||
主題 | GATA-2 | |||||
キーワード | ||||||
言語 | en | |||||
主題 | transcription factor | |||||
キーワード | ||||||
言語 | en | |||||
主題 | Zn finger | |||||
資源タイプ | ||||||
資源タイプ | journal article | |||||
著者 |
Ezomo, Ojeiru F
× Ezomo, Ojeiru F× Takahashi, Kazuya× Horie, Yuki× Mustak, Mohammed S× Meshitsuka, Shunsuke× Takahashi, Kazuya× Horie, Yuki× Mustak, Mohammed S |
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著者所属 | ||||||
値 | Division of Integrative Bioscience, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University | |||||
著者所属 | ||||||
値 | Division of Integrative Bioscience, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University | |||||
著者所属 | ||||||
値 | Division of Integrative Bioscience, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University | |||||
著者所属 | ||||||
値 | Division of Integrative Bioscience, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University | |||||
著者所属 | ||||||
値 | Division of Integrative Bioscience, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University | |||||
抄録 | ||||||
内容記述タイプ | Other | |||||
内容記述 | The C-terminal zinc finger domain of GATA-2 transcription factor from Rattus norvegicus has been expressed and purified to elucidate its secondary structure using circular dichroism spectroscopy. Circular dichroism spectra showed that native GATA-2 C-terminal domain of (Cys)4 type zinc finger has 12% α-helix, 36% β-sheet and 52% random coil content. The estimated structure was compared with predicted structures by sequence based prediction software SOPMA and found to be similar. Furthermore, the effect of pH on the secondary structure of GATA-2 C-finger was examined. This study provides an insight into the understanding of the structure and function of transcription factor GATA-2. | |||||
書誌情報 |
Yonago Acta medica en : Yonago Acta medica 巻 53, 号 1, p. 25-28, 発行日 2010-03 |
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出版者 | ||||||
出版者 | Tottori University Faculty of Medicine | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13468049 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00892882 | |||||
権利 | ||||||
権利情報 | Yonago Acta medica 編集委員会 | |||||
情報源 | ||||||
関連名称 | Yonago Acta medica. 2010, 53(1), 25-28 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |