| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2018-06-22 |
| タイトル |
|
|
タイトル |
Clinical Findings on Fibroblast Activation Protein in Patients with Gastric Cancer |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
fibroblast activation protein |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
gastric cancer |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
immunohistochemistry |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
prognosis |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
fibroblast activation protein |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
gastric cancer |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
immunohistochemistry |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
prognosis |
| 資源タイプ |
|
|
資源タイプ |
journal article |
| 著者 |
Fukumoto, Yoji
Yamada, Yoshinori
Fukuda, Kenji
Saito, Hiroaki
Tatebe, Shigeru
Tsujitani, Shunichi
Ikeguchi, Masahide
Yamada, Yoshinori
Fukuda, Kenji
Tatebe, Shigeru
Tsujitani, Shunichi
|
| 著者所属 |
|
|
値 |
Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine |
| 著者所属 |
|
|
値 |
Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine |
| 著者所属 |
|
|
値 |
Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine |
| 著者所属 |
|
|
値 |
Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine |
| 著者所属 |
|
|
値 |
Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine |
| 著者所属 |
|
|
値 |
Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine |
| 著者所属 |
|
|
値 |
Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine |
| 著者所属（英） |
|
|
言語 |
en |
|
値 |
Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, Tottori University |
| 抄録 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Human fibroblast activation protein (FAP) is a 97-kDa surface glycoprotein expressed in tumor-associated fibroblasts. In this study, we immunohistochemically examined FAP levels in surgically resected gastric carcinomas and explored their association with clini-copathological findings and prognosis. Sections of paraffin-embedded specimens were obtained from 100 patients with advanced gastric cancer between 1989 and 2001 at our institution, and they were stained with an anti-FAP antibody. Expression of FAP was detected in 64 patients (64%). Lymphatic vessel invasion was observed in 90% of FAP-positive patients (P = 0.015). Blood vessel invasion was observed in 98% of FAP-positive patients (P < 0.001). The disease-specific 5-year survival rate of in the 64 patients with FAP-positive tumors (22%) was significantly lower than in the 36 patients with FAP-negative tumors (34%, P = 0.036). This indicates that vessel invasion is connected with the expression of FAP and that a positive finding of FAP confer a worse prognosis in the patients with gastric cancer. |
| 書誌情報 |
Yonago Acta medica
en : Yonago Acta medica
巻 52,
号 1,
p. 21-25,
発行日 2009-03
|
| 出版者 |
|
|
出版者 |
Tottori University Faculty of Medicine |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13468049 |
| 書誌レコードID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00892882 |
| 権利 |
|
|
権利情報 |
Yonago Acta medica 編集委員会 |
| 情報源 |
|
|
|
関連名称 |
Yonago Acta medica. 2009, 52(1), 21-25 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
52_021-025.pdf (169.6 kB)
