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EBV-Associated Diseases in Humans and their Animal in vivo Models: Part I
https://repository.lib.tottori-u.ac.jp/records/5075
https://repository.lib.tottori-u.ac.jp/records/50758cf79f20-2d39-4da8-a345-23dfd9683fd6
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
48_001-006.pdf (239.1 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2018-06-22 | |||||
| タイトル | ||||||
| タイトル | EBV-Associated Diseases in Humans and their Animal in vivo Models: Part I | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | animal mode | |||||
| キーワード | ||||||
| 主題 | EBV-associated disease | |||||
| キーワード | ||||||
| 主題 | human; lymphocryptovirus | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | animal mode | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | EBV-associated disease | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | human; lymphocryptovirus | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
Hayashi, Kazuhiko
× Hayashi, Kazuhiko |
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| 著者所属 | ||||||
| 値 | Division of Molecular Pathology, Department of Microbiology and Pathology, School of Medicine, Tottori University Faculty of Medicine | |||||
| 抄録 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Epstein-Barr virus (EBV) is one of human herpesviruses and a member of the gamma herpesvirus family (lymphocryptovirus). Infectious mononucleosis, Burkitt's lymphoma and nasopharyngeal carcinoma are well-known EBV-associated diseases. The range of EBV-associated diseases has recently expanded to include Hodgkin's lymphoma, T-cell lymphoma, pyothorax-associated or methotrexate-associated B-cell lymphoma, primary effusion lymphoma and lymphoepithelioma-like carcinoma of the stomach, thymus and salivary gland, lymphoproliferative disorders (LPDs) or leiomyosarcomas from immunocompromized host, oral hairy leukoplakia and EBV-associated hemophagocytic syndrome. Animal models of human EBV-associated diseases are essential to elucidate the pathogenesis of EBV-infection and EBV-associated diseases. However, only several reports on the animal models of EBV infection have been reported. Here I review the summary of EBV-associated diseases in humans and those previous animal models using EBV or EBV-like herpesviruses and describe some details on our two newly developed rabbit models of LPD induced by simian EBV-like viruses and a mouse model with murine gammaherpesvirus. These animal models are useful and inexpensive alternative experimental model systems for studying the biology and pathogenesis of EBV, and prophylactic and therapeutic regimens. | |||||
| 書誌情報 |
Yonago Acta medica en : Yonago Acta medica 巻 48, 号 1, p. 1-6, 発行日 2005-03 |
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| 出版者 | ||||||
| 出版者 | Tottori University Faculty of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 13468049 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00892882 | |||||
| 権利 | ||||||
| 権利情報 | Yonago Acta medica 編集委員会 | |||||
| 情報源 | ||||||
| 関連名称 | Yonago Acta medica. 2005, 48(1), 1-6 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
