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Effect of Long-Term Estrogen Replacement on Bladder Function in Old Female Rats
https://repository.lib.tottori-u.ac.jp/records/5078
https://repository.lib.tottori-u.ac.jp/records/50786d6ef5f0-7b38-4159-885c-e0bec6fea900
名前 / ファイル | ライセンス | アクション |
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48_027-031.pdf (146.2 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2018-06-22 | |||||
タイトル | ||||||
タイトル | Effect of Long-Term Estrogen Replacement on Bladder Function in Old Female Rats | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題 | bladder function | |||||
キーワード | ||||||
主題 | estrogen | |||||
キーワード | ||||||
主題 | rat | |||||
キーワード | ||||||
言語 | en | |||||
主題 | bladder function | |||||
キーワード | ||||||
言語 | en | |||||
主題 | estrogen | |||||
キーワード | ||||||
言語 | en | |||||
主題 | rat | |||||
資源タイプ | ||||||
資源タイプ | journal article | |||||
著者 |
Kobayashi, Naoto
× Kobayashi, Naoto× Hikita, Katsuya× Miyagawa, Ikuo× Kobayashi, Naoto |
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著者所属 | ||||||
値 | Division of Urology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||
著者所属 | ||||||
値 | Division of Urology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||
著者所属 | ||||||
値 | Division of Urology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||
抄録 | ||||||
内容記述タイプ | Other | |||||
内容記述 | The effects of estradiol (E2) on urodynamic parameters were studied with twenty 16-month-old female Wistar rats. They were divided into 4 groups, i.e., Group I: untreated; Groups II and III: treated with E2 for 4 and 8 weeks, respectively; Group IV: treated with a placebo for 8 weeks. After treatment, we measured their plasma E2 levels, and recorded their voiding behavior for 24 h. Cystometry was performed and urodynamic parameters were analyzed. Particularly, bladder capacity as well as voided volume and frequency were surveyed. The results obtained were compared among groups. Levels of bladder capacity in the E2-replaced groups (Groups II, 0.52 ± 0.14 mL and Groups III, 0.58 ± 0.09 mL) were significantly (P < 0.05) higher than in the other groups (Group I, 0.38 ± 0.09 mL and Group IV, 0.40 ± 0.11 mL) respectively. The average voided volume was significantly (P < 0.05) higher in the E2-replaced groups (Groups II, 1.06 ± 0.22 mL and Groups III, 1.01 ± 0.16 mL) than in Group IV (0.79 ± 0.15 mL), respectively. Concerning the number of daily micturition per day, a significant difference (P < 0.05) was observed only between Group III (14.2 ± 2.7) and Group IV (18.8 ± 3.7). This suggests that E2-replacement therapy positively affects bladder function. | |||||
書誌情報 |
Yonago Acta medica en : Yonago Acta medica 巻 48, 号 1, p. 27-31, 発行日 2005-03 |
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出版者 | ||||||
出版者 | Tottori University Faculty of Medicine | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13468049 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00892882 | |||||
権利 | ||||||
権利情報 | Yonago Acta medica 編集委員会 | |||||
情報源 | ||||||
関連名称 | Yonago Acta medica. 2005, 48(1), 27-31 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |