Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2018-06-22 |
タイトル |
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言語 |
en |
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タイトル |
Increased Activity of 2',5'-Oligoadenylate Synthetase in Peripheral Blood Mononuclear Cells of Patients with Major Depressive Disorder |
言語 |
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言語 |
eng |
キーワード |
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主題Scheme |
Other |
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主題 |
interferon |
キーワード |
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主題Scheme |
Other |
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主題 |
major depressive disorder |
キーワード |
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主題Scheme |
Other |
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主題 |
2',5'-oligoadenylate synthetase |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
interferon |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
major depressive disorder |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
2',5'-oligoadenylate synthetase |
資源タイプ |
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資源タイプ |
journal article |
著者 |
Yamada, Takeshi
Ikuta, Kazufumi
Kawahara, Ryuzo
Sairenji, Takeshi
Yamada, Takeshi
Ikuta, Kazufumi
Kawahara, Ryuzo
Sairenji, Takeshi
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著者所属 |
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Division of Neoropsychiatry, Department of Multidisciplinary Internal Medicine, School of Medicine, Tottori University Faculty of Medicine |
著者所属 |
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Division of Biosignaling, Department of Biomedical Sciences, School of Life Sciences, Tottori University Faculty of Medicine |
著者所属 |
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Division of Neoropsychiatry, Department of Multidisciplinary Internal Medicine, School of Medicine, Tottori University Faculty of Medicine |
著者所属 |
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Division of Biosignaling, Department of Biomedical Sciences, School of Life Sciences, Tottori University Faculty of Medicine |
抄録 |
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内容記述タイプ |
Other |
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内容記述 |
The aim of this study was to measure the activity of 2',5'-oligoadenylate synthetase (2',5'AS) which is mainly induced by interferon (IFN)-α and -β in patients with major depression and evaluate its relationship to the disease. 2',5'AS activity of 23 patients (male = 11, female = 12) with major depression and of 29 normal control subjects (male = 15, female = 14) was measured in peripheral blood mononuclear cells (PBMCs) by radioassay. The mean 2',5'AS activity in the PBMCs of the patients and that of the control subjects were 1.10 ± 0.69% and 0.72 ± 0.51%, respectively. The activity in the patients was statistically higher than that of the control subjects (P = 0.03). These results imply some abnormality in the IFN-2',5'AS system of patients with major depression. |
書誌情報 |
Yonago Acta medica
en : Yonago Acta medica
巻 47,
号 1,
p. 1-5,
発行日 2004-03
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出版者 |
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出版者 |
Tottori University Faculty of Medicine |
ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
13468049 |
書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA00892882 |
権利 |
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権利情報 |
Yonago Acta medica 編集委員会 |
情報源 |
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関連名称 |
Yonago Acta medica. 2004, 47(1), 1-5 |
著者版フラグ |
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出版タイプ |
VoR |