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Immunohistochemical Detection of Occult Serosal Microinvasion in Primary Lesions of Gastric Cancer with Subserosal Invasion
https://repository.lib.tottori-u.ac.jp/records/5114
https://repository.lib.tottori-u.ac.jp/records/5114728a74c9-70ea-4c7c-8d4f-c877521a7034
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
46_125-131.pdf (196.8 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2018-06-22 | |||||
| タイトル | ||||||
| タイトル | Immunohistochemical Detection of Occult Serosal Microinvasion in Primary Lesions of Gastric Cancer with Subserosal Invasion | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | cytokeratin | |||||
| キーワード | ||||||
| 主題 | gastric cancer with subserosal invasion | |||||
| キーワード | ||||||
| 主題 | hematoxylin-eosin staining | |||||
| キーワード | ||||||
| 主題 | immunohistochemical staining | |||||
| キーワード | ||||||
| 主題 | serosal microinvasion | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | cytokeratin | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | gastric cancer with subserosal invasion | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | hematoxylin-eosin staining | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | immunohistochemical staining | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | serosal microinvasion | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
Wei, Zheng Qiang
× Wei, Zheng Qiang× Maeta, Michio× Yoshida, Haruhiko× Ikeguchi, Masahide× Tsujitani, Shunichi× Kaibara, Nobuaki× Wei, Zheng Qiang× Tsujitani, Shunichi |
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| 著者所属 | ||||||
| 値 | Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||
| 著者所属 | ||||||
| 値 | Department of Fundamental Nursing, School of Health Sciences, Tottori University Faculty of Medicine | |||||
| 著者所属 | ||||||
| 値 | Department of Pathobiological Science and Technology, School of Health Sciences, Tottori University Faculty of Medicine | |||||
| 著者所属 | ||||||
| 値 | Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||
| 著者所属 | ||||||
| 値 | Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||
| 著者所属 | ||||||
| 値 | Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine | |||||
| 抄録 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | In gastric cancer, the presence or absence of serosal invasion by cancer in the primary lesion is an important prognostic factor. Pathological findings are routinely determined by hematoxylin-eosin (H&E) staining, but it is well known that micrometastasis or microinvasion are easily overlooked by H&E staining. Cytokeratin (CK) proteins serve as reliable markers for cells from epithelial origins. The purpose of this study was to clarify the usefulness of CK immunohistochemical staining in the detection of serosal microinvasion in gastric cancer with subserosal invasion. We examined 50 primary lesions from 50 gastric cancer patients with subserosal invasion. Two consecutive sections were prepared for simultaneous staining with ordinary H&E and CK immunostaining with anticytokeratin antibody (CAM 5.2), respectively. Although there were no differences in the postoperative survival rates between patients with or without microinvasion, serosal microinvasion was 0detected in 8 (16%) of 50 patients by CK staining, including 1 patient whose invasion was detected by both H&E and CK stainings. CK immunostaining enabled us to make an accurate and detailed diagnosis which we believe to be useful for detecting serosal microinvasion in the primary lesion in gastric cancer with subserosal invasion. | |||||
| 書誌情報 |
Yonago Acta medica en : Yonago Acta medica 巻 46, 号 4, p. 125-131, 発行日 2003-12 |
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| 出版者 | ||||||
| 出版者 | Tottori University Faculty of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 13468049 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00892882 | |||||
| 権利 | ||||||
| 権利情報 | Yonago Acta medica 編集委員会 | |||||
| 情報源 | ||||||
| 関連名称 | Yonago Acta medica. 2003, 46(4), 125-131 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
