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Genomic Organization of the Human Arpp Gene
https://repository.lib.tottori-u.ac.jp/records/5116
https://repository.lib.tottori-u.ac.jp/records/51164e328d1c-7d0d-49a0-8137-a45f413d6eff
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
45_001-008.pdf (120.4 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-06-22 | |||||
| タイトル | ||||||
| タイトル | Genomic Organization of the Human Arpp Gene | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | Arpp | |||||
| キーワード | ||||||
| 主題 | Carp | |||||
| キーワード | ||||||
| 主題 | E box | |||||
| キーワード | ||||||
| 主題 | heart | |||||
| キーワード | ||||||
| 主題 | skeletal muscle | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | Arpp | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | Carp | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | E box | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | heart | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | skeletal muscle | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
Miyazaki, Akiko
× Miyazaki, Akiko× Tsukamoto, Yoshiyuki× Sato, Kenzo× Ohgi, Shigetsugu× Moriyama, Masatsugu× Miyazaki, Akiko× Tsukamoto, Yoshiyuki× Moriyama, Masatsugu |
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| 著者所属 | ||||||
| 値 | Department of Molecular Biology, and Second Department of Surgery, Tottori University Faculty of Medicine | |||||
| 著者所属 | ||||||
| 値 | Department of Molecular Biology, Tottori University Faculty of Medicine | |||||
| 著者所属 | ||||||
| 値 | Department of Molecular Biology, Tottori University Faculty of Medicine | |||||
| 著者所属 | ||||||
| 値 | Second Department of Surgery, Tottori University Faculty of Medicine | |||||
| 著者所属 | ||||||
| 値 | Department of Molecular Biology, Tottori University Faculty of Medicine | |||||
| 抄録 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | A novel ankyrin-repeated protein, Arpp, is specifically expressed in skeletal and cardiac muscles. Arpp protein is homologous, in its amino acid sequences (52.7% identity), to Carp protein which is proposed to be a putative genetic marker for cardiac hypertrophy. In this study, we isolated the human Arpp gene by screening a human genomic library and analyzed the genomic structure and its 5' flanking region. The Arpp gene was found to encompass a sequence of 11 kb and to consist of 9 exons. The translational initiation site and the stop codon were found to be located at exon 1 and exon 9, respectively. Each exon from 5 to 8 was found to encode 1 of the 4 ankyrin-like domains, respectively. The 2.7 kb upstream of exon 1 was sequenced. The TATA box was identified 29 bp upstream of the transcriptional start site, and multiple putative regulatory elements including the E box and upstream stimulating factor-1 were distributed within the proximal promoter regions. Since these elements were also found in the promoter region of the mouse Arpp gene, they may play an important role in the transcriptional regulation of both human and murine Arpp genes. | |||||
| 書誌情報 |
Yonago Acta medica en : Yonago Acta medica 巻 45, 号 1, p. 1-8, 発行日 2002-03 |
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| 出版者 | ||||||
| 出版者 | Tottori University Faculty of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 13468049 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00892882 | |||||
| 権利 | ||||||
| 権利情報 | Yonago Acta medica 編集委員会 | |||||
| 情報源 | ||||||
| 関連名称 | Yonago Acta medica. 2002, 45(1), 1-8 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
