| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2018-06-22 |
| タイトル |
|
|
タイトル |
Persistence of Acquired Epileptogenesis in Amygdaloid-Kindled Rats: Relationship between the Initial Kindling Stages and Seizure Development in Rekindling |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
amygdaloid kindling |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
epileptogenesis |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
partial seizure |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
rat |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
rekindling |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
amygdaloid kindling |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
epileptogenesis |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
partial seizure |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
rat |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
rekindling |
| 資源タイプ |
|
|
資源タイプ |
journal article |
| 著者 |
Takeo, Shigeki
Yoshioka, Shin-ichi
Maeda, Kazuhisa
Takasu, Junji
Ueda, Toshiyuki
Kawahara, Ryuzo
Takeo, Shigeki
Maeda, Kazuhisa
Takasu, Junji
Ueda, Toshiyuki
Kawahara, Ryuzo
|
| 著者所属 |
|
|
値 |
Department of Neuro-Psychiatry, Faculty of Medicine, Tottori University |
| 著者所属 |
|
|
値 |
Department of Neuro-Psychiatry, Faculty of Medicine, Tottori University |
| 著者所属 |
|
|
値 |
Department of Neuro-Psychiatry, Faculty of Medicine, Tottori University |
| 著者所属 |
|
|
値 |
Department of Neuro-Psychiatry, Faculty of Medicine, Tottori University |
| 著者所属 |
|
|
値 |
Department of Neuro-Psychiatry, Faculty of Medicine, Tottori University |
| 著者所属 |
|
|
値 |
Department of Neuro-Psychiatry, Faculty of Medicine, Tottori University |
| 抄録 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
In order to gain insight into mechanisms underlying the persistence of the partial kindling effect, we suspended amygdaloid kindling at different seizure stages in rats, and investigated the effects on subsequent rekindling after a rest period of 2 months. Ten-week-old rats, implanted with bipolar electrodes, were separated by various initial kindling stages into 5 groups of rats, partially kindled to stages 1 (n = 7) and 2 (n = 10), fully kindled to stages 4 (n = 11) and 5 (n = 11), and control rats (n = 12) which were implanted but not stimulated initially. The number of stimulations required to elicit the first stage 5 seizure during rekindling was significantly lower in the fully kindled groups (P < 0.01 in the stage 4 group and P < 0.001 in the stage 5 group) than the control group. The cumulative afterdischarge duration during rekindling was significantly shorter in the fully kindled groups (P < 0.01 in both groups) than the control group. The latency of the first stage 5 seizure during rekindling was significantly shorter in the partially and fully kindled groups than the control group. These results suggest that epileptogenesis acquired at the partially kindled stage is different than that acquired at the fully kindled stage. However, the effects of the initial kindling on the latency to produce the stage 5 seizure during rekindling persisted both in the partially and fully kindled rats. |
| 書誌情報 |
Yonago Acta medica
en : Yonago Acta medica
巻 43,
号 3,
p. 95-101,
発行日 2000-11
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| 出版者 |
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|
出版者 |
Tottori University Faculty of Medicine |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
13468049 |
| 書誌レコードID |
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収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00892882 |
| 権利 |
|
|
権利情報 |
Yonago Acta medica 編集委員会 |
| 情報源 |
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|
関連名称 |
Yonago Acta medica. 2000, 43(3), 95-101 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
43_095-101.pdf (48.4 kB)
