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Ameliorated Outcome of Subarachnoid Hemorrhage Patients Treated with Reduced Form Glutathione
https://repository.lib.tottori-u.ac.jp/records/5205
https://repository.lib.tottori-u.ac.jp/records/5205357879c8-6ee1-4db6-acc7-ba146f47409a
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
41_073-081.pdf (37.3 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-06-22 | |||||
| タイトル | ||||||
| タイトル | Ameliorated Outcome of Subarachnoid Hemorrhage Patients Treated with Reduced Form Glutathione | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | glutathione | |||||
| キーワード | ||||||
| 主題 | lipid peroxide | |||||
| キーワード | ||||||
| 主題 | patient outcome | |||||
| キーワード | ||||||
| 主題 | subarachnoid hemorrhage | |||||
| キーワード | ||||||
| 主題 | vasospasm | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | glutathione | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | lipid peroxide | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | patient outcome | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | subarachnoid hemorrhage | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | vasospasm | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
Okamoto, Hisayo
× Okamoto, Hisayo× Takeuchi, Hirochika× Tanabe, Michiharu× Akatsuka, Keiichi× Nishiyama, Makoto× Watanabe, Takashi× Hori, Tomokatsu× Okamoto, Hisayo× Takeuchi, Hirochika× Tanabe, Michiharu× Akatsuka, Keiichi× Nishiyama, Makoto× Watanabe, Takashi× Hori, Tomokatsu |
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| 著者所属 | ||||||
| 値 | Division of Neurosurgery, Institute of Neurological Sciences, Faculty of Medicine, Tottori University | |||||
| 著者所属 | ||||||
| 値 | Division of Neurosurgery, Institute of Neurological Sciences, Faculty of Medicine, Tottori University | |||||
| 著者所属 | ||||||
| 値 | Division of Neurosurgery, Institute of Neurological Sciences, Faculty of Medicine, Tottori University | |||||
| 著者所属 | ||||||
| 値 | Division of Neurosurgery, Institute of Neurological Sciences, Faculty of Medicine, Tottori University | |||||
| 著者所属 | ||||||
| 値 | Division of Neurosurgery, Institute of Neurological Sciences, Faculty of Medicine, Tottori University | |||||
| 著者所属 | ||||||
| 値 | Division of Neurosurgery, Institute of Neurological Sciences, Faculty of Medicine, Tottori University | |||||
| 著者所属 | ||||||
| 値 | Division of Neurosurgery, Institute of Neurological Sciences, Faculty of Medicine, Tottori University | |||||
| 抄録 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | This study was designed to investigate the effects of glutathione (GSH) on delayed vasospasm and the outcome of subarachnoid hemorrhage (SAH) patients. Seventy-seven SAH patients who were admitted to 4 hospitals and operated on within 72 h after SAH, were injected intravenously with GSH (2.4 g/day) every 6 h for 14 days. Seventy SAH patients who were not treated with GSH in the same period were selected as the control group. Patient background, the outcome at 3 months after SAH according to the Glasgow Outcome Scale and the occurrence of symptomatic vasospasm were investigated. There were no statistically significant differences in patient backgrounds between the 2 groups. Regarding patient outcome, 57 patients (74%) showed good recovery, 8 (10%) were moderately disabled, 9 (12%) were severely disabled, 2 (3%) were in vegetative survival and 1 (1%) died in the GSH group, versus 39 (56%), 9 (13%), 15 (21%), 3 (4%) and 4 (6%) in the control group, respectively. These overall outcomes in the GSH group were significantly better than those in the control group (P < 0.05). In the GSH group, 31 patients (40%) showed symptomatic vasospasm, significantly lower than 46 (66%) in the control group (P < 0.01). Administration of GSH could be a good treatment for SAH patients. | |||||
| 書誌情報 |
Yonago Acta medica en : Yonago Acta medica 巻 41, 号 2, p. 73-81, 発行日 1998-07 |
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| 出版者 | ||||||
| 出版者 | Tottori University Faculty of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 13468049 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00892882 | |||||
| 権利 | ||||||
| 権利情報 | Yonago Acta medica 編集委員会 | |||||
| 情報源 | ||||||
| 関連名称 | Yonago Acta medica. 1998, 41(2), 73-81 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
