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Cytokeratin-Positive Cells in Lymph Nodes in Which Metastases Are Undetectable by Conventional Histological Staining in Advanced Gastric Cancer
https://repository.lib.tottori-u.ac.jp/records/5209
https://repository.lib.tottori-u.ac.jp/records/52095834cb28-15ea-46d4-a71d-32869dd8dbdd
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
41_105-112.pdf (217.8 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-06-22 | |||||
| タイトル | ||||||
| タイトル | Cytokeratin-Positive Cells in Lymph Nodes in Which Metastases Are Undetectable by Conventional Histological Staining in Advanced Gastric Cancer | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | cytokeratin | |||||
| キーワード | ||||||
| 主題 | gastric cancer | |||||
| キーワード | ||||||
| 主題 | lymph nodes | |||||
| キーワード | ||||||
| 主題 | micrometastases | |||||
| キーワード | ||||||
| 主題 | prognosis | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | cytokeratin | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | gastric cancer | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | lymph nodes | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | micrometastases | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | prognosis | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
Maeta, Michio
× Maeta, Michio× Cai, Jianhui× Oka, Shinichi× Saito, Hiroaki× Kondo, Akira× Tsujitani, Shunichi× Ikeguchi, Masahide× Kaibara, Nobuaki× Cai, Jianhui× Oka, Shinichi× Tsujitani, Shunichi |
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| 著者所属 | ||||||
| 値 | First Department of Surgery, Faculty of Medicine, Tottori University | |||||
| 著者所属 | ||||||
| 値 | First Department of Surgery, Faculty of Medicine, Tottori University | |||||
| 著者所属 | ||||||
| 値 | First Department of Surgery, Faculty of Medicine, Tottori University | |||||
| 著者所属 | ||||||
| 値 | First Department of Surgery, Faculty of Medicine, Tottori University | |||||
| 著者所属 | ||||||
| 値 | First Department of Surgery, Faculty of Medicine, Tottori University | |||||
| 著者所属 | ||||||
| 値 | First Department of Surgery, Faculty of Medicine, Tottori University | |||||
| 著者所属 | ||||||
| 値 | First Department of Surgery, Faculty of Medicine, Tottori University | |||||
| 著者所属 | ||||||
| 値 | First Department of Surgery, Faculty of Medicine, Tottori University | |||||
| 抄録 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Detection of occult metastases in lymph nodes by immunostaining is becoming of increasing interest as a way to improve the accuracy of predicting the prognosis for patients with gastric cancer. Immunohistochemical detection of cytokeratin (CK) is recognized as the most sensitive method for identification of cancerous epithelial cells. In this study, lymph nodes were stained for CK in an effort to detect micrometastases and the clinical implications of the results were examined. We immunostained sections from a total of 1,198 lymph nodes from 25 totally gastrectomized patients with T3 or T4 gastric cancer who had been diagnosed as having no nodal involvement by conventional hematoxylin-eosin (HE) staining. Eighty (6.7%) of 1,198 lymph nodes from 15 (60%) of the 25 patients were immunostained with a CK-specific monoclonal antibody. CK-positive cells were more frequent in patients with macroscopic types of 3,4 and 5 gastric cancer. Patients with nodes that were both HE-negative and CK-negative had the best postoperative survival, followed by patients with HE-negative and CK-positive nodes and, finally, by patiof micrometastases in lymph nodes is a reliable indicator of the prognosis of patients with advanced gastric cancer. | |||||
| 書誌情報 |
Yonago Acta medica en : Yonago Acta medica 巻 41, 号 3, p. 105-112, 発行日 1998-11 |
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| 出版者 | ||||||
| 出版者 | Tottori University Faculty of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 13468049 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00892882 | |||||
| 権利 | ||||||
| 権利情報 | Yonago Acta medica 編集委員会 | |||||
| 情報源 | ||||||
| 関連名称 | Yonago Acta medica. 1998, 41(3), 105-112 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
