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LL55: Selective Early Lymphoid Expression of a Murine cDNA Clone Which Encodes a Putative RNA-Binding Protein
https://repository.lib.tottori-u.ac.jp/records/5211
https://repository.lib.tottori-u.ac.jp/records/5211d00c478f-d3f5-47ec-927d-79ec1b8e84d8
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
2009-06-05 (61.6 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2018-06-22 | |||||
| タイトル | ||||||
| タイトル | LL55: Selective Early Lymphoid Expression of a Murine cDNA Clone Which Encodes a Putative RNA-Binding Protein | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | B cell | |||||
| キーワード | ||||||
| 主題 | cDNA clone (LL55) | |||||
| キーワード | ||||||
| 主題 | fetal development | |||||
| キーワード | ||||||
| 主題 | mRNA splicing | |||||
| キーワード | ||||||
| 主題 | RNP | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | B cell | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | cDNA clone (LL55) | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | fetal development | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | mRNA splicing | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | RNP | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
Baba, Takashi
× Baba, Takashi× Mitsuyoshi, Saori× Igarashi, Hideya× Sakaguchi, Nobuo× Mitsuyoshi, Saori× Igarashi, Hideya× Sakaguchi, Nobuo |
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| 著者所属 | ||||||
| 値 | Department of Immunology and Department of Ophthalmology, Faculty of Medicine, Tottori University | |||||
| 著者所属 | ||||||
| 値 | Department of Immunology, Kumamoto University School of Medicine | |||||
| 著者所属 | ||||||
| 値 | Department of Immunology, Kumamoto University School of Medicine | |||||
| 著者所属 | ||||||
| 値 | Department of Immunology, Kumamoto University School of Medicine | |||||
| 抄録 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Specific expression of various RNA-binding protein (RNP) molecules is one of the critical factors that determine the development in Drosophila melanogaster and Caenorhabditis elegans. In the present study, we found a complementary DNA clone, LL55 encoding a putative RNP. Structural comparison of nucleotide and amino acid sequences demonstrate that LL55 encoding a nuclear protein with two RNA-binding consensus motifs and the common arginine-serine repeats, is similar to the sex-determining transformer-2 (tra-2) gene of Drosophila melanogaster. The expression of 2.3 kilobase (kb) and 1.5 kb LL55 messenger RNA (mRNA) is ubiquitous in murine organs and tissues, but it is selective in the early development of fetal life. It appears as early as day 10.5 and increases until day 15 of gestation in accordance with the expression of λ5 mRNA which is involved in murine pre-B cell generation. Taking account of the selective expression and the specific regulation of RNP molecules, the finding of LL55 RNP provides a new outlook for the generation and function of the immune system. | |||||
| 書誌情報 |
Yonago Acta medica en : Yonago Acta medica 巻 40, 号 2, p. 97-106, 発行日 1997-07 |
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| 出版者 | ||||||
| 出版者 | Tottori University Faculty of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 13468049 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00892882 | |||||
| 権利 | ||||||
| 権利情報 | Yonago Acta medica 編集委員会 | |||||
| 情報源 | ||||||
| 関連名称 | Yonago Acta medica. 1997, 40(2), 97-106 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
