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Sox2 in the adult rat sensory nervous system
https://repository.lib.tottori-u.ac.jp/records/7204
https://repository.lib.tottori-u.ac.jp/records/7204fce677ae-8ddb-4fcb-be66-ed2342f7b3f0
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
hcb141(3)_301.pdf (20.1 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2020-01-15 | |||||
| タイトル | ||||||
| タイトル | Sox2 in the adult rat sensory nervous system | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | Sox2 | |||||
| キーワード | ||||||
| 主題 | Peripheral nervous system | |||||
| キーワード | ||||||
| 主題 | Satellite glial cell | |||||
| キーワード | ||||||
| 主題 | Schwann cell | |||||
| キーワード | ||||||
| 主題 | Immunohistochemistry | |||||
| キーワード | ||||||
| 主題 | Rat | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | Sox2 | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | Peripheral nervous system | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | Satellite glial cell | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | Schwann cell | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | Immunohistochemistry | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | Rat | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
Kioke, Taro
× Kioke, Taro× Wakabayashi, Taketoshi× Mori, Tetsuji× Takamori, Yasuharu× Hirahara, Yukie× Yamada, Hisao |
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| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Department of Anatomy and Cell ScienceKansai Medical University | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Department of Anatomy and Cell ScienceKansai Medical University | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Department of Anatomy and Cell ScienceKansai Medical University | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Department of Anatomy and Cell ScienceKansai Medical University | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Department of Anatomy and Cell ScienceKansai Medical University | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Department of Anatomy and Cell ScienceKansai Medical University | |||||
| 抄録 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Sex-determining region Y (SRY)-box 2 (Sox2) is a member of the Sox family transcription factors. In the central nervous system, Sox2 is expressed in neural stem cells from neurogenic regions, and regulates stem cell proliferation and differentiation. In the peripheral nervous system, Sox2 is found only in the immature and dedifferentiated Schwann cells, and is involved in myelination inhibition or N-cadherin redistribution. In the present immunohistochemical study, we found that Sox2 is also expressed in other cells of the adult rat peripheral nervous system. Nuclear Sox2 was observed in all satellite glial cells, non-myelinating Schwann cells, and the majority of terminal Schwann cells that form lamellar corpuscles and longitudinal lanceolate endings. Sox2 was not found in myelinating Schwann cells and terminal Schwann cells of subepidermal free nerve endings. Satellite glial cells exhibit strong Sox2 immunoreactivity, whereas non-myelinating Schwann cells show weak immunoreactivity. RT-PCR confirmed the presence of Sox2 mRNA, indicating that the cells are likely Sox2 expressors. Our findings suggest that the role of Sox2 in the peripheral nervous system may be cell-type-dependent. | |||||
| 書誌情報 |
Histochemistry and cell biology en : Histochemistry and cell biology 巻 141, 号 3, p. 301-309, 発行日 2013-10-31 |
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| 雑誌内区分 | ||||||
| 値 | Original Paper | |||||
| 出版者 | ||||||
| 出版者 | Springer Berlin Heidelberg | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 09486143 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA11033302 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1007/s00418-013-1158-x | |||||
| 権利 | ||||||
| 権利情報 | © Springer-Verlag Berlin Heidelberg 2013 | |||||
| 情報源 | ||||||
| 関連名称 | This is a post-peer-review, pre-copyedit version of an article published in [ Kioke, T., Wakabayashi, T., Mori, T. et al. Histochem Cell Biol (2014) 141: 301. https://doi.org/10.1007/s00418-013-1158-x ]. The final authenticated version is available online | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://link.springer.com/article/10.1007%2Fs00418-013-1158-x | |||||
| 関連名称 | https://link.springer.com/article/10.1007%2Fs00418-013-1158-x | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
