| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2021-03-09 |
| タイトル |
|
|
タイトル |
Natural course and characteristics of cutaneous neurofibromas in neurofibromatosis 1 |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
cutaneous neurofibroma |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
distribution |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
neurofibromatosis 1 |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
NF1 |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
predilection body site |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
cutaneous neurofibroma |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
distribution |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
neurofibromatosis 1 |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
NF1 |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
predilection body site |
| 資源タイプ |
|
|
資源タイプ |
journal article |
| 著者 |
江原, 由布子
山元, 修
吉田, 雄一
Ehara, Yuko
Kosaki, Kenjiro
|
| 著者所属（英） |
|
|
言語 |
en |
|
値 |
Division of Dermatology, Department of Medicine of Sensory and Motor Organs, Faculty of Medicine,Tottori University |
| 著者所属（英） |
|
|
言語 |
en |
|
値 |
Division of Dermatology, Department of Medicine of Sensory and Motor Organs, Faculty of Medicine, Tottori University |
| 著者所属（英） |
|
|
言語 |
en |
|
値 |
Division of Dermatology, Department of Medicine of Sensory and Motor Organs, Faculty of Medicine, Tottori University |
| 著者所属（英） |
|
|
言語 |
en |
|
値 |
Division of Dermatology, Department of Medicine of Sensory and Motor Organs, Faculty of Medicine, Tottori University |
| 抄録 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Neurofibromatosis 1 (NF1) is characterized by cutaneous, neurological and osseous manifestations. Most NF1 patients develop cutaneous neurofibromas. However, time‐dependent change with aging and the predilection site of cutaneous neurofibromas remain unclear. To clarify the natural course and characteristics of cutaneous neurofibromas, a retrospective study was conducted for 57 NF1 patients who were treated at the Department of Dermatology of Tottori University Hospital between January 2007 and April 2016. For each patient, we investigated the time‐dependent changes and the numbers of cutaneous neurofibromas in four body surface regions. There was a positive correlation between age and number of cutaneous neurofibromas (r = 0.75, P < 0.001). Cutaneous neurofibromas were located on the trunk (60.2%), lower limbs (16.1%), upper limbs (14.4%), and head and neck (9.2%). There was no significant relationship between each body type (e.g. obese or thin) and cutaneous neurofibromas. With respect to the year‐to‐year percentage change in cutaneous neurofibromas, the average annual rate of increase was 0.21 (range, −0.71 to 1.2). The number of cutaneous neurofibromas had increased in approximately 61% of the patients 1 year later. Our data will enable physicians to estimate the overall state of cutaneous neurofibromas in NF1 and will be useful for handling cutaneous manifestations before they become a serious condition. |
| 書誌情報 |
JOURNAL OF DERMATOLOGY
en : JOURNAL OF DERMATOLOGY
巻 45,
号 1,
p. 53-57,
発行日 2018
|
| 出版者 |
|
|
出版者 |
WILEY |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
03852407 |
| 書誌レコードID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00696658 |
| DOI |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1111/1346-8138.14025 |
| 権利 |
|
|
権利情報 |
(C) 2017 Japanese Dermatological Association |
| 情報源 |
|
|
|
関連名称 |
Ehara Yuko, Yamamoto Osamu, Kosaki Kenjiro, et al. Natural course and characteristics of cutaneous neurofibromas in neurofibromatosis 1. JOURNAL OF DERMATOLOGY. 2018. 45(1). 53-57. doi:10.1111/1346-8138.14025 |
| 関連サイト |
|
|
|
識別子タイプ |
URI |
|
|
関連識別子 |
https://onlinelibrary.wiley.com/doi/10.1111/1346-8138.14025 |
|
|
関連名称 |
https://onlinelibrary.wiley.com/doi/10.1111/1346-8138.14025 |
| 著者版フラグ |
|
|
出版タイプ |
AM |
| EISSN |
|
|
値 |
13468138 |
jd45(1)_53.pdf (2.0 MB)
