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Self-assembled artificial viral capsid bearing coiled-coils at the surface
https://repository.lib.tottori-u.ac.jp/records/7319
https://repository.lib.tottori-u.ac.jp/records/73191735b932-e058-44dc-af51-cf07f96bd7a5
| 名前 / ファイル | ライセンス | アクション |
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obc15(23)_5070.pdf (1.9 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||
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| 公開日 | 2018-12-13 | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | Self-assembled artificial viral capsid bearing coiled-coils at the surface | |||||||||||||
| 言語 | en | |||||||||||||
| 言語 | ||||||||||||||
| 言語 | eng | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ | journal article | |||||||||||||
| 著者 |
Fujita, Seiya
× Fujita, Seiya
× Matsuura, Kazunori
× Fujita, Seiya
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| 著者所属 | ||||||||||||||
| 値 | Department of chemistry and Biotechnology, Graduate School of Engineering, Tottori University | |||||||||||||
| 著者所属 | ||||||||||||||
| 値 | Department of chemistry and Biotechnology, Graduate School of Engineering, Tottori University | |||||||||||||
| 著者所属（英） | ||||||||||||||
| 言語 | en | |||||||||||||
| 値 | Department of chemistry and Biotechnology, Graduate School of Engineering, Tottori University | |||||||||||||
| 著者所属（英） | ||||||||||||||
| 言語 | en | |||||||||||||
| 値 | Department of chemistry and Biotechnology, Graduate School of Engineering, Tottori University | |||||||||||||
| 抄録 | ||||||||||||||
| 内容記述タイプ | Other | |||||||||||||
| 内容記述 | In order to construct artificial viral capsids bearing complementary dimeric coiled-coils on the surface, β-annulus peptide bearing a coiled-coil forming sequence at the C-terminus (β-annulus-coiled-coil-B) was synthesized by a native chemical ligation of β-annulus-SBn peptide with Cys-containing coiled-coil-B peptide. Dynamic light scattering (DLS) measurements and transmission electron microscope (TEM) images revealed that the β-annulus-coiled-coil-B peptide self-assembled into spherical structures of about 50 nm in 10 mM Tris-HCl buffer. Circular dichroism (CD) spectra indicated formation of the complementary coiled-coil structure on the spherical assemblies. Addition of 0.25 equivalent of complementary coiled-coil-A peptide to the β-annulus-coiled-coil-B peptide showed the formation of spherical assemblies of 46 ± 14 nm with grains of 5 nm at the surface, whereas addition of 1 equivalent of complementary coiled-coil-A peptide generated fibrous assemblies. | |||||||||||||
| 書誌情報 |
Organic & biomolecular chemistry en : Organic & biomolecular chemistry 巻 15, 号 23, p. 5070-5077, 発行日 2017-05-25 |
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| 出版者 | ||||||||||||||
| 出版者 | Royal Society of Chemistry | |||||||||||||
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| 収録物識別子タイプ | ISSN | |||||||||||||
| 収録物識別子 | 14770520 | |||||||||||||
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| 収録物識別子タイプ | NCID | |||||||||||||
| 収録物識別子 | AA1168650X | |||||||||||||
| DOI | ||||||||||||||
| 関連タイプ | isVersionOf | |||||||||||||
| 識別子タイプ | DOI | |||||||||||||
| 関連識別子 | 10.1039/C7OB00998D | |||||||||||||
| 権利 | ||||||||||||||
| 権利情報 | © The Royal Society of Chemistry 2017 | |||||||||||||
| 情報源 | ||||||||||||||
| 関連名称 | This research was published by Elsevier : Fujita S. and Matsuura K. Self-assembled artificial viral capsid bearing coiled-coils at the surface. Organic & biomolecular chemistry. 2017, 15, 5070-5077. doi: https://doi.org/10.1039/C7OB00998D | |||||||||||||
| 関連サイト | ||||||||||||||
| 識別子タイプ | URI | |||||||||||||
| 関連識別子 | https://pubs.rsc.org/en/content/articlelanding/2017/ob/c7ob00998d | |||||||||||||
| 関連名称 | https://pubs.rsc.org/en/content/articlelanding/2017/ob/c7ob00998d | |||||||||||||
| 著者版フラグ | ||||||||||||||
| 出版タイプ | AM | |||||||||||||
