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Self-assembled artificial viral capsid bearing coiled-coils at the surface
https://repository.lib.tottori-u.ac.jp/records/7319
https://repository.lib.tottori-u.ac.jp/records/73191735b932-e058-44dc-af51-cf07f96bd7a5
名前 / ファイル | ライセンス | アクション |
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obc15(23)_5070.pdf (1.9 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
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公開日 | 2018-12-13 | |||||||||
タイトル | ||||||||||
タイトル | Self-assembled artificial viral capsid bearing coiled-coils at the surface | |||||||||
言語 | en | |||||||||
言語 | ||||||||||
言語 | eng | |||||||||
資源タイプ | ||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
資源タイプ | journal article | |||||||||
著者 |
Fujita, Seiya
× Fujita, Seiya× Matsuura, Kazunori
WEKO
4763
× Fujita, Seiya |
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著者所属 | ||||||||||
値 | Department of chemistry and Biotechnology, Graduate School of Engineering, Tottori University | |||||||||
著者所属 | ||||||||||
値 | Department of chemistry and Biotechnology, Graduate School of Engineering, Tottori University | |||||||||
著者所属(英) | ||||||||||
言語 | en | |||||||||
値 | Department of chemistry and Biotechnology, Graduate School of Engineering, Tottori University | |||||||||
著者所属(英) | ||||||||||
言語 | en | |||||||||
値 | Department of chemistry and Biotechnology, Graduate School of Engineering, Tottori University | |||||||||
抄録 | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | In order to construct artificial viral capsids bearing complementary dimeric coiled-coils on the surface, β-annulus peptide bearing a coiled-coil forming sequence at the C-terminus (β-annulus-coiled-coil-B) was synthesized by a native chemical ligation of β-annulus-SBn peptide with Cys-containing coiled-coil-B peptide. Dynamic light scattering (DLS) measurements and transmission electron microscope (TEM) images revealed that the β-annulus-coiled-coil-B peptide self-assembled into spherical structures of about 50 nm in 10 mM Tris-HCl buffer. Circular dichroism (CD) spectra indicated formation of the complementary coiled-coil structure on the spherical assemblies. Addition of 0.25 equivalent of complementary coiled-coil-A peptide to the β-annulus-coiled-coil-B peptide showed the formation of spherical assemblies of 46 ± 14 nm with grains of 5 nm at the surface, whereas addition of 1 equivalent of complementary coiled-coil-A peptide generated fibrous assemblies. | |||||||||
書誌情報 |
Organic & biomolecular chemistry en : Organic & biomolecular chemistry 巻 15, 号 23, p. 5070-5077, 発行日 2017-05-25 |
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出版者 | ||||||||||
出版者 | Royal Society of Chemistry | |||||||||
ISSN | ||||||||||
収録物識別子タイプ | ISSN | |||||||||
収録物識別子 | 14770520 | |||||||||
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収録物識別子タイプ | NCID | |||||||||
収録物識別子 | AA1168650X | |||||||||
DOI | ||||||||||
関連タイプ | isVersionOf | |||||||||
識別子タイプ | DOI | |||||||||
関連識別子 | 10.1039/C7OB00998D | |||||||||
権利 | ||||||||||
権利情報 | © The Royal Society of Chemistry 2017 | |||||||||
情報源 | ||||||||||
関連名称 | This research was published by Elsevier : Fujita S. and Matsuura K. Self-assembled artificial viral capsid bearing coiled-coils at the surface. Organic & biomolecular chemistry. 2017, 15, 5070-5077. doi: https://doi.org/10.1039/C7OB00998D | |||||||||
関連サイト | ||||||||||
識別子タイプ | URI | |||||||||
関連識別子 | https://pubs.rsc.org/en/content/articlelanding/2017/ob/c7ob00998d | |||||||||
関連名称 | https://pubs.rsc.org/en/content/articlelanding/2017/ob/c7ob00998d | |||||||||
著者版フラグ | ||||||||||
出版タイプ | AM | |||||||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa |