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Identification of NeuN immunopositive cells in the adult mouse subventricular zone
https://repository.lib.tottori-u.ac.jp/records/7383
https://repository.lib.tottori-u.ac.jp/records/7383c3a4756d-387e-4055-820b-7833b2fe4e3d
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
jcn526(12)_1927.pdf (3.6 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2020-01-16 | |||||
| タイトル | ||||||
| タイトル | Identification of NeuN immunopositive cells in the adult mouse subventricular zone | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | adult neurogenesis | |||||
| キーワード | ||||||
| 主題 | heterogenity | |||||
| キーワード | ||||||
| 主題 | neurogenic niche | |||||
| キーワード | ||||||
| 主題 | NeuN | |||||
| キーワード | ||||||
| 主題 | subventricular zone | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | adult neurogenesis | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | heterogenity | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | neurogenic niche | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | NeuN | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | subventricular zone | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
Saito, Kengo
× Saito, Kengo× Koike, Taro× Kawashima, Fumiaki× Kurata, Hirofumi× Shibuya, Taku× Satoh, Takemasa× Hata, Yoshio× Yamada, Hisao× Mori, Tetsuji |
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| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Department of Biological Regulation, School of Health Science, Faculty of Medicine, Tottori University | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Department of Anatomy and Cell Science, Kansai Medical University | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Department of Biological Regulation, School of Health Science, Faculty of Medicine, Tottori University | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Department of Biological Regulation, School of Health Science, Faculty of Medicine, Tottori University / Division of Child Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Division of Integrative Bioscience, Institute of Regenerative Medicine and Biofunction, Tottori University Graduate School of Medical Sciences | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Division of Neurobiology, School of Life Sciences, Faculty of Medicine, Tottori University | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Division of Integrative Bioscience, Institute of Regenerative Medicine and Biofunction, Tottori University Graduate School of Medical Sciences / Division of Neurobiology, School of Life Sciences, Faculty of Medicine, Tottori University | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Department of Anatomy and Cell Science, Kansai Medical University | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Department of Biological Regulation, School of Health Science, Faculty of Medicine, Tottori University | |||||
| 抄録 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | In the adult rodent subventricular zone (SVZ), there are neural stem cells (NSCs) and the specialized neurogenic niche is critical to maintain their stemness. To date, many cellular and noncellular factors that compose the neurogenic niche and markers to identify subpopulations of Type A cells have been confirmed. In particular, neurotransmitters regulate adult neurogenesis and mature neurons in the SVZ have been only partially analyzed. Moreover, Type A cells, descendants of NSCs, are highly heterogeneous and more molecular markers are still needed to identify them. In the present study, we systematically classified NeuN, commonly used as a marker of mature and immature post‐mitotic neurons, immunopositive (+) cells within the adult mouse SVZ. These SVZ‐NeuN+ cells (SVZ‐Ns) were mainly classified into two types. One was mature SVZ‐Ns (M‐SVZ‐Ns). Neurochemical properties of M‐SVZ‐Ns were similar to those of striatal neurons, but their birth date and morphology were different. M‐SVZ‐Ns were generated during embryonic and early postnatal stages with bipolar peaks and extended their processes along the wall of the lateral ventricle. The second type was small SVZ‐Ns (S‐SVZ‐Ns) with features of Type A cells. They expressed not only markers of Type A cells, but also proliferated and migrated from the SVZ to the olfactory bulb. Furthermore, S‐SVZ‐Ns could be classified into two types by their spatial locations and glutamic acid decarboxylase 67 expression. Our data indicate that M‐SVZ‐Ns are a new component of the neurogenic niche and S‐SVZ‐Ns are newly identified subpopulations of Type A cells. | |||||
| 書誌情報 |
The Journal of comparative neurology en : The Journal of comparative neurology 巻 526, 号 12, p. 1927-1942, 発行日 2018-05-11 |
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| 雑誌内区分 | ||||||
| 値 | RESEARCH ARTICLE | |||||
| 出版者 | ||||||
| 出版者 | Wiley Periodicals | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 10969861 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA11628274 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1002/cne.24463 | |||||
| 権利 | ||||||
| 権利情報 | © 2018 Wiley Periodicals, Inc. | |||||
| 情報源 | ||||||
| 関連名称 | This is the peer reviewed version of the following article: Saito, K, Koike, T, Kawashima, F, et al. Identification of NeuN immunopositive cells in the adult mouse subventricular zone. J Comp Neurol. 2018; 526: 1927– 1942. https://doi.org/10.1002/cne.2446 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://onlinelibrary.wiley.com/doi/abs/10.1002/cne.24463 | |||||
| 関連名称 | https://onlinelibrary.wiley.com/doi/abs/10.1002/cne.24463 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
