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Phylogenetic Analysis of Spotted Fever Group Rickettsia Gene from Ticks and Human Patients in Tottori Prefecture, Japan
https://repository.lib.tottori-u.ac.jp/records/7696
https://repository.lib.tottori-u.ac.jp/records/76961b87c7dc-5459-4f33-b1ba-5548afdb9a22
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
yam66(2)_246.pdf (3.3 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2023-07-18 | |||||
| タイトル | ||||||
| タイトル | Phylogenetic Analysis of Spotted Fever Group Rickettsia Gene from Ticks and Human Patients in Tottori Prefecture, Japan | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | Japanese spotted fever | |||||
| キーワード | ||||||
| 主題 | tick | |||||
| キーワード | ||||||
| 主題 | Tottori Prefecture | |||||
| キーワード | ||||||
| 主題 | Rickettsia japonica | |||||
| キーワード | ||||||
| 主題 | Spotted Fever Group Rickettsia | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | Japanese spotted fever | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | tick | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | Tottori Prefecture | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | Rickettsia japonica | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | Spotted Fever Group Rickettsia | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
大槻, 均
× 大槻, 均× 近藤, 陽子× 蓼本, 早百合× 伊藤, 大輔× Tademoto, Sayuri |
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| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Division of Medical Zoology, Department of Microbiology and Immunology, School of Medicine, Faculty of Medicine, Tottori University | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Division of Medical Zoology, Department of Microbiology and Immunology, School of Medicine, Faculty of Medicine, Tottori University | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Technical Department, Tottori University | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Division of Medical Zoology, Department of Microbiology and Immunology, School of Medicine, Faculty of Medicine, Tottori University | |||||
| 著者ID | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 03017 | |||||
| 著者ID | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 04689 | |||||
| 著者ID | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 03539 | |||||
| 著者ID | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 04635 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Background: Japanese spotted fever (JSF) is a tick-borne bacterial febrile disease caused by Rickettsia japonica characterized by fever, rash, and occasional death. The number of patients in Japan and the Tottori Prefecture has been increasing over the past 20 years. Most cases were found in Eastern Tottori; however, the distribution of patients has expanded to the Central and Western regions. Ticks carried by wild animals may be the cause, but the prevalence of R. japonica in ticks has not yet been analyzed. Methods: Ticks were collected by flagging-dragging from 16 sites in Tottori, Japan. The ticks were morphologically classified and DNA was extracted. The 17-kDa antigen gene was amplified using nested PCR. PCR amplicons from ticks and JSF patients were sequenced and phylogenetically compared. Results: In total, 177 ticks were collected and identified as Haemahysalis, Ixodes, Amblyomma, and Dermcentor. The Spotted Fever Group Rickettsia (SFGR) was detected in Haemahysalis and Amblyomma spp. using PCR, with positivity rates of 36.8% and 33.3%, respectively. DNA sequencing and phylogenetic analysis revealed that positive ticks harbored R. japonica, P. raoultii, and other Rickettsiae species; however, the patient’s samples were restricted to R. japonica. Similar to the incidence of JSF, the rate of R. japonica-positive ticks was higher in the Eastern region; however, R. japonica-positive ticks were also detected in the Western region. Conclusion: R. japonica sequences had been found in ticks collected in Tottori Prefecture. Ticks harboring R. japonica were found in the Eastern and Western parts of Tottori Prefecture and the sequences were identical to the human cases. Only the R. japonica sequence has been detected in patients with spotted fever symptoms, even though ticks were harboring various SFGRs. | |||||
| 書誌情報 |
Yonago Acta Medica en : Yonago Acta Medica 巻 66, 号 2, p. 246-256, 発行日 2023-05-25 |
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| 出版者 | ||||||
| 出版者 | Tottori University Medical Press | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 05135710 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00892882 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.33160/yam.2023.05.013 | |||||
| 権利 | ||||||
| 権利情報 | (C) 2023 Tottori University Medical Press. | |||||
| 情報源 | ||||||
| 関連名称 | Yonago Acta Medica. 2023, 66(2), 246-256. doi10.33160/yam.2023.05.013 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.lib.tottori-u.ac.jp/yam/yam/yam66-2/66-2contents.html | |||||
| 関連名称 | https://www.lib.tottori-u.ac.jp/yam/yam/yam66-2/66-2contents.html | |||||
| 関連サイト | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.33160/yam.2023.05.013 | |||||
| 関連名称 | https://doi.org/10.33160/yam.2023.05.013 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| EISSN | ||||||
| 値 | 13468049 | |||||
