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Is Adjuvant Chemotherapy Necessary in Patients with Early Endometrial Cancer?
https://repository.lib.tottori-u.ac.jp/records/4633
https://repository.lib.tottori-u.ac.jp/records/4633417b3b99-930d-4528-a335-3d96c307c76b
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
yam65(1)_82.pdf (1.9 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||
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| 公開日 | 2022-03-09 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Is Adjuvant Chemotherapy Necessary in Patients with Early Endometrial Cancer? | |||||||||||
| 言語 | en | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| キーワード | ||||||||||||
| 主題 | endometrial cancer | |||||||||||
| キーワード | ||||||||||||
| 主題 | lymphovascular space invasion | |||||||||||
| キーワード | ||||||||||||
| 主題 | prognosis | |||||||||||
| キーワード | ||||||||||||
| 主題 | recurrent risk | |||||||||||
| キーワード | ||||||||||||
| 言語 | en | |||||||||||
| 主題 | endometrial cancer | |||||||||||
| キーワード | ||||||||||||
| 言語 | en | |||||||||||
| 主題 | lymphovascular space invasion | |||||||||||
| キーワード | ||||||||||||
| 言語 | en | |||||||||||
| 主題 | prognosis | |||||||||||
| キーワード | ||||||||||||
| 言語 | en | |||||||||||
| 主題 | recurrent risk | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ | journal article | |||||||||||
| 著者 |
野坂, 加苗
× 野坂, 加苗× 佐藤, 慎也× 大石, 徹郎× 谷口, 文紀
WEKO
3792
× 原田, 省× Iida, Yuki× Komatsu, Hiroaki× Okawa, Masayo× Osaku, Daiken |
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| 著者所属（英） | ||||||||||||
| 言語 | en | |||||||||||
| 値 | Division of Obstetrics and Gynecology, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University | |||||||||||
| 著者所属（英） | ||||||||||||
| 言語 | en | |||||||||||
| 値 | Division of Obstetrics and Gynecology, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University | |||||||||||
| 著者所属（英） | ||||||||||||
| 言語 | en | |||||||||||
| 値 | Division of Obstetrics and Gynecology, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University | |||||||||||
| 著者所属（英） | ||||||||||||
| 言語 | en | |||||||||||
| 値 | Division of Obstetrics and Gynecology, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University | |||||||||||
| 著者所属（英） | ||||||||||||
| 言語 | en | |||||||||||
| 値 | Department of Pathology, School of Medicine, Faculty of Medicine, Tottori University | |||||||||||
| 著者所属（英） | ||||||||||||
| 言語 | en | |||||||||||
| 値 | Division of Obstetrics and Gynecology, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University | |||||||||||
| 著者所属（英） | ||||||||||||
| 言語 | en | |||||||||||
| 値 | Division of Obstetrics and Gynecology, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University | |||||||||||
| 著者所属（英） | ||||||||||||
| 言語 | en | |||||||||||
| 値 | Division of Obstetrics and Gynecology, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University | |||||||||||
| 著者所属（英） | ||||||||||||
| 言語 | en | |||||||||||
| 値 | Division of Obstetrics and Gynecology, Department of Surgery, School of Medicine, Faculty of Medicine, Tottori University | |||||||||||
| 抄録 | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 内容記述 | Background: We investigated whether there was a difference in prognosis between patients with stage IA endometrial cancer with and without lymphovascular space invasion. Methods: We enrolled patients with stage IA (pT1aN0M0) endometrial cancer admitted to our hospital from 2009 to 2018. All patients underwent hysterectomy, bilateral salpingo-oophorectomy, and systematic pelvic lymphadenectomy. We immunopathologically evaluated the presence or absence of lymphovascular space invasion in the tumor tissue using hematoxylin and eosin, Elastica-van Gieson, and podoplanin staining. We analyzed disease-free and overall survival and calculated patients’ survival distribution using the Kaplan–Meier method and log-rank test. The multivariate analysis was performed to determine the prognostic factors. Results: A total of 116 patients were included. The median age of the patients was 57 (range, 30–78) years, and the histological subtype revealed 98 and 18 cases of types 1 and 2, respectively. The median follow-up period was 71.9 (range, 10.8–149) months, and the 3-year disease-free and 3-year overall survival rates were 94% and 99%, respectively. The disease-free and overall survival rates were significantly shorter in type 2 patients than in type 1 patients (type 2 vs. type 1; 77% vs. 97%, P < 0.01, 94% vs. 100%, P = 0.014, respectively). The univariate and multivariate analyses showed that there were no significant differences in disease-free survival between the lymphovascular space invasion-positive and -negative groups among type 1 cases. Conclusion: There was no difference in prognosis between patients with stage IA and type 1 endometrial cancer with and without lymphovascular space invasion. | |||||||||||
| 書誌情報 |
Yonago Acta Medica en : Yonago Acta Medica 巻 65, 号 1, p. 82-87, 発行日 2022-02-22 |
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| 出版者 | ||||||||||||
| 出版者 | Tottori University Medical Press | |||||||||||
| ISSN | ||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||
| 収録物識別子 | 05135710 | |||||||||||
| 書誌レコードID | ||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||
| 収録物識別子 | AA00892882 | |||||||||||
| DOI | ||||||||||||
| 関連タイプ | isIdenticalTo | |||||||||||
| 識別子タイプ | DOI | |||||||||||
| 関連識別子 | 10.33160/yam.2022.02.014 | |||||||||||
| 権利 | ||||||||||||
| 権利情報 | (C) 2022 Tottori University Medical Press. | |||||||||||
| 情報源 | ||||||||||||
| 関連名称 | Yonago Acta Medica. 2022, 65(1), 82-87. doi:10.33160/yam.2022.02.014 | |||||||||||
| 関連サイト | ||||||||||||
| 識別子タイプ | URI | |||||||||||
| 関連識別子 | https://www.lib.tottori-u.ac.jp/yam/yam/yam65-1/65-1contents.html | |||||||||||
| 関連名称 | https://www.lib.tottori-u.ac.jp/yam/yam/yam65-1/65-1contents.html | |||||||||||
| 関連サイト | ||||||||||||
| 識別子タイプ | DOI | |||||||||||
| 関連識別子 | https://doi.org/10.33160/yam.2022.02.014 | |||||||||||
| 関連名称 | https://doi.org/10.33160/yam.2022.02.014 | |||||||||||
| 著者版フラグ | ||||||||||||
| 出版タイプ | VoR | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
| EISSN | ||||||||||||
| 値 | 13468049 | |||||||||||
