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Clinical and Biological Implications of Cancer Stem Cells in Hepatocellular Carcinoma
https://repository.lib.tottori-u.ac.jp/records/4665
https://repository.lib.tottori-u.ac.jp/records/4665e26b3e60-af31-41e8-9f7d-c9c6f1769c16
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
yam64(1)_001.pdf (824.8 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2021-03-17 | |||||
| タイトル | ||||||
| タイトル | Clinical and Biological Implications of Cancer Stem Cells in Hepatocellular Carcinoma | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | cancer stem cells | |||||
| キーワード | ||||||
| 主題 | cell surface markers | |||||
| キーワード | ||||||
| 主題 | hepatocellular carcinoma | |||||
| キーワード | ||||||
| 主題 | lncRNA | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | cancer stem cells | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | cell surface markers | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | hepatocellular carcinoma | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | lncRNA | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
土谷, 博之
× 土谷, 博之× 汐田, 剛史 |
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| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Division of Medical Genetics and Regenerative Medicine, Department of Genomic Medicine and Regenerative Therapy, Faculty of Medicine, Tottori University | |||||
| 著者所属（英） | ||||||
| 言語 | en | |||||
| 値 | Division of Medical Genetics and Regenerative Medicine, Department of Genomic Medicine and Regenerative Therapy, Faculty of Medicine, Tottori University | |||||
| 抄録 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Hepatocellular carcinoma (HCC) is a malignant tumor with poor prognosis, and is one of the leading causes of cancer-related deaths worldwide. Recently, the development of therapeutic drugs via novel mechanisms of action, involving molecular-targeted drugs and immune checkpoint inhibitors, has progressed in the field of HCC. However, the recurrence rate remains high, and further improvement of the prognosis of patients with HCC is urgently needed. Cancer stem cells (CSCs) are a promising target for further development of novel anti-cancer drugs because they are reportedly involved in tumor initiation, maintenance, recurrence, and resistance to conventional therapies. Although several studies have already been conducted, the functions and roles of CSCs in the development and progression of tumors remain to be elucidated. In this review article, we will clarify the fundamental knowledge of CSCs necessary for the understanding of CSCs and will outline so-far identified markers specific to liver CSCs and the pathological and therapeutic implications of CSCs in HCC. | |||||
| 書誌情報 |
Yonago Acta Medica en : Yonago Acta Medica 巻 64, 号 1, p. 1-11, 発行日 2021-02-22 |
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| 出版者 | ||||||
| 出版者 | Tottori University Medical Press | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 05135710 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00892882 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.33160/yam.2021.02.002 | |||||
| 権利 | ||||||
| 権利情報 | (C) 2021 Tottori University Medical Press | |||||
| 情報源 | ||||||
| 関連名称 | H. Tsuchiya, G. Shiota. Clinical and Biological Implications of Cancer Stem Cells in Hepatocellular Carcinoma. Yonago Acta Medica. 2021, 64(1), 1-11. doi:10.33160/yam.2021.02.002 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.lib.tottori-u.ac.jp/yam/yam/yam64-1/64-1contents.html | |||||
| 関連名称 | http://www.lib.tottori-u.ac.jp/yam/yam/yam64-1/64-1contents.html | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.jstage.jst.go.jp/article/yam/64/1/64_2021.02.002/_article/-char/ja | |||||
| 関連名称 | https://www.jstage.jst.go.jp/article/yam/64/1/64_2021.02.002/_article/-char/ja | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| EISSN | ||||||
| 値 | 13468049 | |||||
