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Clinical Effects of Probiotic Bifidobacterium breve Supplementation in Adult Patients with Atopic Dermatitis
https://repository.lib.tottori-u.ac.jp/records/5012
https://repository.lib.tottori-u.ac.jp/records/501297d7053b-c49b-4433-8188-0974f58373a9
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
53_037-045.pdf (122.2 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-06-22 | |||||
| タイトル | ||||||
| タイトル | Clinical Effects of Probiotic Bifidobacterium breve Supplementation in Adult Patients with Atopic Dermatitis | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | allergy | |||||
| キーワード | ||||||
| 主題 | Bifidobacterium | |||||
| キーワード | ||||||
| 主題 | intestinal | |||||
| キーワード | ||||||
| 主題 | probiotics | |||||
| キーワード | ||||||
| 主題 | quality of life | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | allergy | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | Bifidobacterium | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | intestinal | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | probiotics | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | quality of life | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
Yoshida, Yuichi
× Yoshida, Yuichi× Seki, Taizo× Matsunaka, Hiroshi× Watanabe, Tessin× Shindo, Masahisa× Yamada, Nanako× Yamamoto, Osamu× Seki, Taizo× Matsunaka, Hiroshi× Watanabe, Tessin× Shindo, Masahisa |
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| 著者所属 | ||||||
| 値 | Division of Dermatology, Department of Medicine of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine | |||||
| 著者所属 | ||||||
| 値 | Research and Development, Tokiwa Pharmaceutical | |||||
| 著者所属 | ||||||
| 値 | Research and Development, Tokiwa Pharmaceutical | |||||
| 著者所属 | ||||||
| 値 | Division of Dermatology, Department of Medicine of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine | |||||
| 著者所属 | ||||||
| 値 | Division of Dermatology, Department of Medicine of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine | |||||
| 著者所属 | ||||||
| 値 | Division of Dermatology, Department of Medicine of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine | |||||
| 著者所属 | ||||||
| 値 | Division of Dermatology, Department of Medicine of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine | |||||
| 抄録 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Probiotics (live microbial food supplements) have been shown to be effective in allergic diseases, but the potential of probiotics for treatment of adult atopic dermatitis is not clear. The effect of probiotic Bifidobacterium breve (B. breve) for atopic dermatitis was assessed in this study. A total of 24 patients were given either B. breve strain YY or a placebo for 8 weeks. Clinical severity was evaluated by using the severity scoring of atopic dermatitis and quality of life was assessed by Skindex-29-J. In addition, blood and fecal samples were taken before and after the study. The objective severity scoring for atopic dermatitis significantly improved in the probiotic group compared with the placebo group. In the quality of life assessment, the total score showed significant improvement in the probiotic group. The proportion of B. breve in intestinal microflora was increased in the probiotic group. However, no significant change in thymus and activation-regulated chemokine (TARC/CCL17), immunoglobulin E or the number of eosinophils was found. Our results suggest that B. breve may be beneficial for the treatment of atopic dermatitis. However, since the severity of disease symptoms in the placebo group at the beginning of the study was milder than those in the probiotic group because the number of patients in the present pilot study was relatively small, further study is needed to determine the clinical value of B. breve in adult patients with atopic dermatitis. | |||||
| 書誌情報 |
Yonago Acta medica en : Yonago Acta medica 巻 53, 号 2, p. 37-45, 発行日 2010-06 |
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| 出版者 | ||||||
| 出版者 | Tottori University Faculty of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 13468049 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00892882 | |||||
| 権利 | ||||||
| 権利情報 | Yonago Acta medica 編集委員会 | |||||
| 情報源 | ||||||
| 関連名称 | Yonago Acta medica. 2010, 53(2), 37-45 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.lib.tottori-u.ac.jp/yam/yam53-2/yam53_037-045.html | |||||
| 関連名称 | https://www.lib.tottori-u.ac.jp/yam/yam53-2/yam53_037-045.html | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
