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Relationship between an Angiotensinogen Gene Polymorphism (M235T) and Serum Lipids: A Cross-Sectional Study among Japanese Workers
https://repository.lib.tottori-u.ac.jp/records/5068
https://repository.lib.tottori-u.ac.jp/records/50687c82ba54-4b5e-49af-b069-c90805383b59
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
49_049-058.pdf (108.4 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2018-06-22 | |||||
| タイトル | ||||||
| タイトル | Relationship between an Angiotensinogen Gene Polymorphism (M235T) and Serum Lipids: A Cross-Sectional Study among Japanese Workers | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | angiotensinogen | |||||
| キーワード | ||||||
| 主題 | polymorphism (genetics) | |||||
| キーワード | ||||||
| 主題 | cholesterol | |||||
| キーワード | ||||||
| 主題 | cross-sectional study | |||||
| キーワード | ||||||
| 主題 | Japanese workers | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | angiotensinogen | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | polymorphism (genetics) | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | cholesterol | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | cross-sectional study | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | Japanese workers | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
Kaetsu, Akihiko
× Kaetsu, Akihiko× Kishimoto, Takuji× Osaki, Yoneatsu× Okamoto, Mikizoh× Kurozawa, Yoichi |
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| 著者所属 | ||||||
| 値 | Division of Environmental and Preventive Medicine, Tottori University Faculty of Medicine | |||||
| 著者所属 | ||||||
| 値 | Division of Environmental and Preventive Medicine, Tottori University Faculty of Medicine | |||||
| 著者所属 | ||||||
| 値 | Division of Environmental and Preventive Medicine, Tottori University Faculty of Medicine | |||||
| 著者所属 | ||||||
| 値 | Division of Environmental and Preventive Medicine, Tottori University Faculty of Medicine | |||||
| 著者所属 | ||||||
| 値 | Division of Health Administration and Promotion, Department of Social Medicine, School of Medicine, Tottori University Faculty of Medicine | |||||
| 抄録 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Angiotensinogen (AGT) is a component of the renin-angiotensin system, which plays a central role in blood pressure regulation. Although it is controversial, the association between AGT gene polymorphisms and hypertension, and coronary heart disease is suspected. In a case-control study on the metabolic syndrome, an association between AGT M235T polymorphism and serum total cholesterol (TC) level was demonstrated by Thomas et al. (2001). To reconfirm this relationship, a cross-sectional study among Japanese workers with 876 dyslipidemia and 1,158 non-dyslipidemia subjects was carried out. To evaluate the AGT M235T polymorphism, a PCR-mutant allele specific amplification (MASA) method was employed. No significant difference in the distribution of genetic variance was observed between the two groups. Although it was not significant, the T allele correlating to the lower TC of the present study occurred in a reversed manner to the previous report. In our results, no significant association between AGT M235T and TC was observed. | |||||
| 書誌情報 |
Yonago Acta medica en : Yonago Acta medica 巻 49, 号 1, p. 49-58, 発行日 2006-03 |
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| 出版者 | ||||||
| 出版者 | Tottori University Faculty of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 13468049 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00892882 | |||||
| 権利 | ||||||
| 権利情報 | Yonago Acta medica 編集委員会 | |||||
| 情報源 | ||||||
| 関連名称 | Yonago Acta medica. 2006, 49(1), 49-58 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
