{"_buckets": {"deposit": "6f9b5459-d642-4a02-95bd-5cd306beb8e6"}, "_deposit": {"created_by": 10, "id": "5068", "owners": [10], "pid": {"revision_id": 0, "type": "depid", "value": "5068"}, "status": "published"}, "_oai": {"id": "oai:repository.lib.tottori-u.ac.jp:00005068", "sets": ["12", "9", "1059"]}, "author_link": ["1203", "1561", "2981", "2880", "1839"], "item_10001_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2006-03", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "58", "bibliographicPageStart": "49", "bibliographicVolumeNumber": "49", "bibliographic_titles": [{"bibliographic_title": "Yonago Acta medica"}, {"bibliographic_title": "Yonago Acta medica", "bibliographic_titleLang": "en"}]}]}, "item_10001_checkbox_27": {"attribute_name": "部局名", "attribute_value_mlt": [{"subitem_checkbox_item": ["i-gakubu"]}]}, "item_10001_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Angiotensinogen (AGT) is a component of the renin-angiotensin system, which plays a central role in blood pressure regulation. Although it is controversial, the association between AGT gene polymorphisms and hypertension, and coronary heart disease is suspected. In a case-control study on the metabolic syndrome, an association between AGT M235T polymorphism and serum total cholesterol (TC) level was demonstrated by Thomas et al. (2001). To reconfirm this relationship, a cross-sectional study among Japanese workers with 876 dyslipidemia and 1,158 non-dyslipidemia subjects was carried out. To evaluate the AGT M235T polymorphism, a PCR-mutant allele specific amplification (MASA) method was employed. No significant difference in the distribution of genetic variance was observed between the two groups. Although it was not significant, the T allele correlating to the lower TC of the present study occurred in a reversed manner to the previous report. 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Angiotensinogen Gene Polymorphism (M235T) and Serum Lipids: A Cross-Sectional Study among Japanese Workers"], "weko_shared_id": -1}