{"_buckets": {"deposit": "15766728-bca9-43c3-9344-02395ba47675"}, "_deposit": {"created_by": 10, "id": "5144", "owners": [10], "pid": {"revision_id": 0, "type": "depid", "value": "5144"}, "status": "published"}, "_oai": {"id": "oai:repository.lib.tottori-u.ac.jp:00005144", "sets": ["12", "9", "1085"]}, "author_link": ["4502", "19096", "3391", "1103", "19097", "19098", "19099"], "item_10001_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2001-07", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "123", "bibliographicPageStart": "115", "bibliographicVolumeNumber": "44", "bibliographic_titles": [{"bibliographic_title": "Yonago Acta medica"}, {"bibliographic_title": "Yonago Acta medica", "bibliographic_titleLang": "en"}]}]}, "item_10001_checkbox_27": {"attribute_name": "部局名", "attribute_value_mlt": [{"subitem_checkbox_item": ["i-gakubu"]}]}, "item_10001_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Leiomyosarcoma (LMS) of soft-tissue origin was studied on the expression and the biological significance of apoptosis in relation to p53 oncoprotein. Immunohistochemical analysis was performed initially on the paraffin-embbeded sections taken from 29 surgical tissues (20 cases) including 9 recurrent/metastatic tumors. The results are as follows: A positive correlation was observed between the p53 indices (PIs) and the proliferative markers designated by Ki-67, PCNA and MCM2, both of which increased significantly in the high-grade malignant LMS much more than in the low-grade one (P \u003c 0.001). Apoptotic cells were detected by the TUNEL method and evaluated as the apoptotic index (AI). A high AI-level was shown in the high-grade malignant LMS, especially in cases of the recurrent/metastatic sites in comparison with the tumors of the primary site (P \u003c 0.05). The AI was statistically higher in the p53-positive cases of high-grade malignant LMS than in the p53-negative cases of low-grade malignant LMS. In conclusion, apoptotic activity paralleled the overexpression of p53 protein along with an increasing grade of malignancy and may be related intimately to the increased malignant potential, especially to recurrence/metastasis.", "subitem_description_type": "Other"}]}, "item_10001_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Tottori University Faculty of Medicine"}]}, "item_10001_relation_16": {"attribute_name": "情報源", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "Yonago Acta medica. 2001, 44(2), 115-123"}]}]}, "item_10001_rights_15": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "Yonago Acta medica　編集委員会"}]}, "item_10001_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00892882", "subitem_source_identifier_type": "NCID"}]}, "item_10001_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "13468049", "subitem_source_identifier_type": "ISSN"}]}, "item_10001_text_25": {"attribute_name": "EARMAS ID", "attribute_value_mlt": [{"subitem_text_value": "829"}]}, "item_10001_text_29": {"attribute_name": "最新掲載誌名", "attribute_value_mlt": [{"subitem_text_value": "yam;Yonago Acta medica;Yonago Acta medica"}]}, "item_10001_text_32": {"attribute_name": "著者所属", "attribute_value_mlt": [{"subitem_text_value": "Department of Pathobiological Science and Technology, Tottori University Faculty of Medicine"}, {"subitem_text_value": "First Department of Pathology, Tottori University Faculty of Medicine"}, {"subitem_text_value": "First Department of Pathology, Tottori University Faculty of Medicine"}, {"subitem_text_value": "First Department of Pathology, Tottori University Faculty of Medicine"}, {"subitem_text_value": "Department of Orthopaedic Surgery, Tottori University Faculty of Medicine"}]}, "item_10001_version_type_20": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Yoshida, Haruhiko"}, {"creatorName": "Yoshida, Haruhiko", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "4502", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "40037429", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=40037429"}]}, {"creatorNames": [{"creatorName": "Watanabe, Mari"}], "nameIdentifiers": [{"nameIdentifier": "19096", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shomori, Kohei"}, {"creatorName": "Shomori, Kohei", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "3391", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "60314572", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=60314572"}]}, {"creatorNames": [{"creatorName": "Ito, Hisao"}, {"creatorName": "Ito, Hisao", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "1103", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "60127610", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=60127610"}]}, {"creatorNames": [{"creatorName": "Minamizaki, Takeshi"}], "nameIdentifiers": [{"nameIdentifier": "19097", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Watanabe, Mari", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "19098", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Minamizaki, Takeshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "19099", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2009-06-08"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "44_115-123.pdf", "filesize": [{"value": "441.8 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensefree": "Yonago Acta medica　編集委員会", "licensetype": "license_note", "mimetype": "application/pdf", "size": 441800.0, "url": {"label": "44_115-123.pdf", "url": "https://repository.lib.tottori-u.ac.jp/record/5144/files/44_115-123.pdf"}, "version_id": "0285ae20-f9a5-4d1d-8693-edc83ec7c5f9"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "apoptosis/immunohistochemistry/leiomyosarcoma/p53 protein", "subitem_subject_scheme": "Other"}, {"subitem_subject": "apoptosis/immunohistochemistry/leiomyosarcoma/p53 protein", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Apoptotic Cell Death and p53 Expression in Leiomyosarcoma of Soft-Tissue Origin", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Apoptotic Cell Death and p53 Expression in Leiomyosarcoma of Soft-Tissue Origin", "subitem_title_language": "en"}]}, "item_type_id": "10001", "owner": "10", "path": ["12", "9", "1085"], "permalink_uri": "https://repository.lib.tottori-u.ac.jp/records/5144", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2018-06-22"}, "publish_date": "2018-06-22", "publish_status": "0", "recid": "5144", "relation": {}, "relation_version_is_last": true, "title": ["Apoptotic Cell Death and p53 Expression in Leiomyosarcoma of Soft-Tissue Origin"], "weko_shared_id": -1}