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Factors Inducing Vascularization Improve the Spermatogenic and Steroidogenic Function of the Varicocelized Testis
https://repository.lib.tottori-u.ac.jp/records/5170
https://repository.lib.tottori-u.ac.jp/records/51706027966b-8561-4703-af16-ed3f1533c176
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
42_041-049.pdf (158.8 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-06-22 | |||||
| タイトル | ||||||
| タイトル | Factors Inducing Vascularization Improve the Spermatogenic and Steroidogenic Function of the Varicocelized Testis | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | growth factors | |||||
| キーワード | ||||||
| 主題 | testis | |||||
| キーワード | ||||||
| 主題 | spermatozoa | |||||
| キーワード | ||||||
| 主題 | varicocele | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | growth factors | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | testis | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | spermatozoa | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題 | varicocele | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
Isoyama, Tadahiro
× Isoyama, Tadahiro× Sofikitis, Nikolaos× Isoyama, Tadahiro× Sofikitis, Nikolaos |
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| 著者所属 | ||||||
| 値 | Department of Urology, Faculty of Medicine, Tottori University | |||||
| 著者所属 | ||||||
| 値 | Department of Urology, Faculty of Medicine, Tottori University | |||||
| 抄録 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | We evaluated whether alterations in testicular vascularization and fluid dynamics have a role in the development of testicular damage in varicocelized animals. Left varicocele was induced in 6 groups of rats (A, B, C, D, E and F; 7 rats in each group). Four times a week, rats of group A, B, C, D, E and F underwent intrascrotal injections of saline, insulin-like growth factor-I, fibroblast growth factor, tumor necrosis factor-α, vascular endothelial growth factor or all the previous factors together, respectively. Additionally 7 rats were sham-operated (group G). At 8 weeks post-operation, groups E, F and G showed significantly higher left epididymal sperm content and motility, testosterone responses to human chorionic gonadotropin stimulation and intraabdominal versus intratesticular temperature differences than group A. Histological sections showed that the number of vessels per seminiferous tubule was significantly larger in groups E and F than in group A. Factors inducing vascularization have a beneficial effect on the function of the varicocelized testis attributable to improvement of testicular tissue nutrition or to amelioration of the functionality of the countercurrent heat exchange system. | |||||
| 書誌情報 |
Yonago Acta medica en : Yonago Acta medica 巻 42, 号 1, p. 41-49, 発行日 1999-03 |
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| 出版者 | ||||||
| 出版者 | Tottori University Faculty of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 13468049 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00892882 | |||||
| 権利 | ||||||
| 権利情報 | Yonago Acta medica 編集委員会 | |||||
| 情報源 | ||||||
| 関連名称 | Yonago Acta medica. 1999, 42(1), 41-49 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
