{"_buckets": {"deposit": "ed109fc7-6449-42aa-b72c-c44cf2fe840d"}, "_deposit": {"created_by": 10, "id": "7097", "owners": [10], "pid": {"revision_id": 0, "type": "depid", "value": "7097"}, "status": "published"}, "_oai": {"id": "oai:repository.lib.tottori-u.ac.jp:00007097", "sets": ["12", "10"]}, "author_link": ["26246", "4648", "4673", "4763", "26247", "26248"], "item_10001_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2020-11", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "22", "bibliographicVolumeNumber": "10", "bibliographic_titles": [{"bibliographic_title": "APPLIED SCIENCES"}, {"bibliographic_title": "APPLIED SCIENCES", "bibliographic_titleLang": "en"}]}]}, "item_10001_checkbox_27": {"attribute_name": "部局名", "attribute_value_mlt": [{"subitem_checkbox_item": ["kou-gakubu"]}]}, "item_10001_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Messenger RNA (mRNA) drugs have attracted considerable attention as promising tools with many therapeutic applications. The efficient delivery of mRNA drugs using non-viral materials is currently being explored. We demonstrate a novel concept where mCherry mRNA bearing a poly(A) tail is encapsulated into capsids co-assembled from viral β-annulus peptides bearing a 20-mer oligothymine (dT20) at the N-terminus and unmodified peptides via hybridization of dT20 and poly(A). Dynamic light scattering measurements and transmission electron microscopy images of the mRNA-encapsulated capsids show the formation of spherical assemblies of approximately 50 nm. The encapsulated mRNA shows remarkable ribonuclease resistance. Further, modification by a cell-penetrating peptide (His16) on the capsid enables the intracellular expression of mCherry of encapsulated mRNA.", "subitem_description_type": "Other"}]}, "item_10001_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "MDPI"}]}, "item_10001_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.3390/app10228004", "subitem_relation_type_select": "DOI"}}]}, "item_10001_relation_16": {"attribute_name": "情報源", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "Nakamura Yoko, Sato Yuki, Inaba Hiroshi, et al. Encapsulation of mRNA into Artificial Viral Capsids via Hybridization of a β-Annulus-dT20 Conjugate and the Poly(A) Tail of mRNA. APPLIED SCIENCES-BASEL. 2020. 10(22). doi:10.3390/app10228004"}]}]}, "item_10001_relation_17": {"attribute_name": "関連サイト", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "https://www.mdpi.com/2076-3417/10/22/8004"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://www.mdpi.com/2076-3417/10/22/8004", "subitem_relation_type_select": "URI"}}]}, "item_10001_rights_15": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "(C) 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)."}]}, "item_10001_text_25": {"attribute_name": "EARMAS ID", "attribute_value_mlt": [{"subitem_text_value": "11464"}]}, "item_10001_text_26": {"attribute_name": "EISSN", "attribute_value_mlt": [{"subitem_text_value": "20763417"}]}, "item_10001_text_33": {"attribute_name": "著者所属（英）", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University"}, {"subitem_text_language": "en", "subitem_text_value": "Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University"}, {"subitem_text_language": "en", "subitem_text_value": "Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University / Centre for Research on Green Sustainable Chemistry, Tottori University"}, {"subitem_text_language": "en", "subitem_text_value": "Department of Bioresources Science, Graduate School of Agricultural Sciences, Tottori University"}, {"subitem_text_language": "en", "subitem_text_value": "Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University / Centre for Research on Green Sustainable Chemistry, Tottori University"}]}, "item_10001_version_type_20": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "ナカムラ, ヨウコ", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "26246", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "稲葉, 央"}, {"creatorName": "イナバ, ヒロシ", "creatorNameLang": "ja-Kana"}, {"creatorName": "Inaba, Hiroshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "4648", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "00778011", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=00778011"}, {"nameIdentifier": "100001643", "nameIdentifierScheme": "研究者総覧鳥取大学", "nameIdentifierURI": "http://researchers.adm.tottori-u.ac.jp/html/100001643_ja.html"}]}, {"creatorNames": [{"creatorName": "岩崎, 崇"}, {"creatorName": "イワサキ, タカシ", "creatorNameLang": "ja-Kana"}, {"creatorName": "Iwasaki, Takashi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "4673", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "30585584", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=30585584"}, {"nameIdentifier": "100000598", "nameIdentifierScheme": "研究者総覧鳥取大学", "nameIdentifierURI": "http://researchers.adm.tottori-u.ac.jp/html/100000598_ja.html"}]}, {"creatorNames": [{"creatorName": "松浦, 和則"}, {"creatorName": "マツウラ, カズノリ", "creatorNameLang": "ja-Kana"}, {"creatorName": "Matsuura, Kazunori", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "4763", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "60283389", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=60283389"}, {"nameIdentifier": "100000881", "nameIdentifierScheme": "研究者総覧鳥取大学", "nameIdentifierURI": "http://researchers.adm.tottori-u.ac.jp/html/100000881_ja.html"}]}, {"creatorNames": [{"creatorName": "Nakamura, Yoko", "creatorNameLang": "en"}, {"creatorName": "ナカムラ, ヨウコ", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "26247", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sato, Yuki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "26248", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2023-03-17"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "as10(22)_app10228004.pdf", "filesize": [{"value": "3.0 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensefree": "(C) 2020 by the authors. 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