| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2021-12-15 |
| タイトル |
|
|
タイトル |
Efficacy of second and subsequent lines of chemotherapy for recurrent and metastatic head and neck cancer |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Recurrent and metastatic |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Head and neck cancer |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Second-line |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Successive |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Chemotherapy |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Recurrent and metastatic |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Head and neck cancer |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Second-line |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Successive |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Chemotherapy |
| 資源タイプ |
|
|
資源タイプ |
journal article |
| 著者 |
小山, 哲史
藤原, 和典
三宅, 成智
福原, 隆宏
竹内, 裕美
Morisaki, Tsuyoshi
|
| 著者所属（英） |
|
|
言語 |
en |
|
値 |
Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine |
| 著者所属（英） |
|
|
言語 |
en |
|
値 |
Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine |
| 著者所属（英） |
|
|
言語 |
en |
|
値 |
Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine |
| 著者所属（英） |
|
|
言語 |
en |
|
値 |
Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine |
| 著者所属（英） |
|
|
言語 |
en |
|
値 |
Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine |
| 著者所属（英） |
|
|
言語 |
en |
|
値 |
Department of Otolaryngology Head and Neck Surgery, Tottori University Faculty of Medicine |
| 抄録 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
ObjectiveThe increase in treatment options resulted in successful treatment with multiple lines of chemotherapy for recurrent and metastatic (RM) head and neck cancer (HNC). The present study aimed to elucidate the beneficial effect of successive treatment for RM-HNC. MethodsWe included 78 patients with RM-HNC who received one or multiple lines of chemotherapy from January 2008 to December 2019. We divided the patients into three groups according to treatment period: January 2008 to November 2012 included those who underwent cancer chemotherapy only with cytotoxic agents (Tox group), December 2012 to March 2017 included those who received cytotoxic agents and cetuximab (Cet group), and March 2017 to December 2019 included those who received cytotoxic agents, cetuximab and immune checkpoint inhibitor nivolumab (Nivo group). Moreover, we compared the overall survival of the three groups. ResultsIn total, 18, 33, and 27 patients were included in the Tox, Cet, and Nivo groups, respectively. The median overall survival were 8.5 months in the Tox group, 16 months in the Cet group, and 19 months in the Nivo group, and the difference in the result was significant. ConclusionsSuccessive treatment with second and subsequent lines of chemotherapy in patients with RM-HNC improves prognosis. |
| 書誌情報 |
Auris Nasus Larynx
en : Auris Nasus Larynx
巻 48,
号 1,
p. 161-165,
発行日 2021-02
|
| 出版者 |
|
|
出版者 |
Elsevier B.V. |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
03858146 |
| DOI |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1016/j.anl.2020.07.016 |
| 権利 |
|
|
権利情報 |
© 2020 Oto-Rhino-Laryngological Society of Japan Inc. Published by Elsevier B.V. All rights reserved. |
| 情報源 |
|
|
|
関連名称 |
Koyama, Satoshi. Fujiwara, Kazunori. Morisaki, Tsuyoshi. et al. Efficacy of second and subsequent lines of chemotherapy for recurrent and metastatic head and neck cancer. Auris Nasus Larynx. 2021. 48(1), 161-165. |
| 関連サイト |
|
|
|
識別子タイプ |
URI |
|
|
関連識別子 |
https://www.sciencedirect.com/science/article/pii/S0385814620301978 |
|
|
関連名称 |
https://www.sciencedirect.com/science/article/pii/S0385814620301978 |
| 著者版フラグ |
|
|
出版タイプ |
AM |
anl48(1)_161.pdf (592.7 kB)
