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Body mass index >= 23 is a risk factor for insulin resistance and diabetes in Japanese people: A brief report
https://repository.lib.tottori-u.ac.jp/records/7339
https://repository.lib.tottori-u.ac.jp/records/733951bcc4c4-c0fe-48c6-bc3c-56713792b89b
| 名前 / ファイル | ライセンス | アクション |
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po13(7)_journal_pone_0201052.pdf (2.6 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||||||
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| 公開日 | 2021-09-15 | |||||||||||||||||
| タイトル | ||||||||||||||||||
| タイトル | Body mass index >= 23 is a risk factor for insulin resistance and diabetes in Japanese people: A brief report | |||||||||||||||||
| 言語 | en | |||||||||||||||||
| 言語 | ||||||||||||||||||
| 言語 | eng | |||||||||||||||||
| 資源タイプ | ||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||
| 著者 |
大倉, 毅
× 大倉, 毅× 藤岡, 洋平× 角, 啓佑× 松澤, 和彦× 伊澤, 正一郎
WEKO
1167
× 上田, 悦子× 加藤, 雅彦× 今村, 武史× 谷口, 晋一
WEKO
3805
× 山本, 一博× Nakamura, Risa× Kawamoto-Kitao, Sonoko× Ito, Yuichi× Matsumoto, Kazuhisa× Shoji, Kyoko× Sumi, Keisuke |
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| 著者所属（英） | ||||||||||||||||||
| 言語 | en | |||||||||||||||||
| 値 | Division of Cardiovascular Medicine, Endocrinology and Metabolism, Tottori University Faculty of Medicine | |||||||||||||||||
| 著者所属（英） | ||||||||||||||||||
| 言語 | en | |||||||||||||||||
| 値 | Division of Cardiovascular Medicine, Endocrinology and Metabolism, Tottori University Faculty of Medicine | |||||||||||||||||
| 著者所属（英） | ||||||||||||||||||
| 言語 | en | |||||||||||||||||
| 値 | Division of Cardiovascular Medicine, Endocrinology and Metabolism, Tottori University Faculty of Medicine | |||||||||||||||||
| 著者所属（英） | ||||||||||||||||||
| 言語 | en | |||||||||||||||||
| 値 | Division of Cardiovascular Medicine, Endocrinology and Metabolism, Tottori University Faculty of Medicine | |||||||||||||||||
| 著者所属（英） | ||||||||||||||||||
| 言語 | en | |||||||||||||||||
| 値 | Division of Cardiovascular Medicine, Endocrinology and Metabolism, Tottori University Faculty of Medicine | |||||||||||||||||
| 著者所属（英） | ||||||||||||||||||
| 言語 | en | |||||||||||||||||
| 値 | Division of Cardiovascular Medicine, Endocrinology and Metabolism, Tottori University Faculty of Medicine | |||||||||||||||||
| 著者所属（英） | ||||||||||||||||||
| 言語 | en | |||||||||||||||||
| 値 | Division of Cardiovascular Medicine, Endocrinology and Metabolism, Tottori University Faculty of Medicine | |||||||||||||||||
| 著者所属（英） | ||||||||||||||||||
| 言語 | en | |||||||||||||||||
| 値 | Division of Cardiovascular Medicine, Endocrinology and Metabolism, Tottori University Faculty of Medicine | |||||||||||||||||
| 著者所属（英） | ||||||||||||||||||
| 言語 | en | |||||||||||||||||
| 値 | Division of Cardiovascular Medicine, Endocrinology and Metabolism, Tottori University Faculty of Medicine | |||||||||||||||||
| 著者所属（英） | ||||||||||||||||||
| 言語 | en | |||||||||||||||||
| 値 | Division of Cardiovascular Medicine, Endocrinology and Metabolism, Tottori University Faculty of Medicine | |||||||||||||||||
| 著者所属（英） | ||||||||||||||||||
| 言語 | en | |||||||||||||||||
| 値 | School of Health Science, Tottori University Faculty of Medicine | |||||||||||||||||
| 著者所属（英） | ||||||||||||||||||
| 言語 | en | |||||||||||||||||
| 値 | Division of Cardiovascular Medicine, Endocrinology and Metabolism, Tottori University Faculty of Medicine | |||||||||||||||||
| 著者所属（英） | ||||||||||||||||||
| 言語 | en | |||||||||||||||||
| 値 | Division of Molecular Pharmacology, Tottori University Faculty of Medicine | |||||||||||||||||
| 著者所属（英） | ||||||||||||||||||
| 言語 | en | |||||||||||||||||
| 値 | Department of Regional Medicine, Tottori University Faculty of Medicine | |||||||||||||||||
| 著者所属（英） | ||||||||||||||||||
| 言語 | en | |||||||||||||||||
| 値 | Division of Cardiovascular Medicine, Endocrinology and Metabolism, Tottori University Faculty of Medicine | |||||||||||||||||
| 抄録 | ||||||||||||||||||
| 内容記述タイプ | Other | |||||||||||||||||
| 内容記述 | Background: Screening for undiagnosed type 2 diabetes mellitus is recommended for Asian Americans with a body mass index ≥23. However, the optimal body mass index cut-off score for predicting the risk of diabetes mellitus in Japanese people is not well known. The aim of this study was to determine the best body mass index cut-off score for predicting insulin resistance and diabetes mellitus in the Japanese population. Methods: This study had two parts, a clinical investigation and a retrospective observational investigation. In the clinical part of the study, 58 participants (26 with type 2 diabetes mellitus and 32 non-diabetics) underwent a hyperinsulinemic-euglycemic clamp from which their glucose disposal rate was measured. For the retrospective part of the study, medical check-up data from 88,305 people in the Tottori Prefecture were analyzed for clinical evidence of diabetes mellitus. The optimal BMI cut-off scores for prediction of insulin resistance and diabetes mellitus were determined. Results: In the clamp study, the optimal body mass index cut-off score to predict insulin resistance in non-diabetic patients was 22.7. All participants with type 2 diabetes mellitus were insulin resistant, and the optimal body mass index cut-off score for prediction of severe insulin resistance was 26.2. When the data from the type 2 diabetic and the non-diabetic participants were combined, the optimal body mass index cut-off score for prediction of insulin resistance was 23.5. Analysis of 88,305 medical check-up records yielded an optimal body mass index cut-off score for prediction of diabetes mellitus of 23.6. Conclusions: These results suggest that having a body mass index ≥23 is a risk factor for insulin resistance and diabetes mellitus in the Japanese population. | |||||||||||||||||
| 書誌情報 |
PLOS ONE en : PLOS ONE 巻 13, 号 7, 発行日 2018-07-20 |
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| 出版者 | Public Library of Science | |||||||||||||||||
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| 収録物識別子タイプ | ISSN | |||||||||||||||||
| 収録物識別子 | 19326203 | |||||||||||||||||
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| 関連タイプ | isIdenticalTo | |||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||
| 関連識別子 | 10.1371/journal.pone.0201052 | |||||||||||||||||
| 権利 | ||||||||||||||||||
| 権利情報 | Copyright: © 2018 Okura et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ar | |||||||||||||||||
| 情報源 | ||||||||||||||||||
| 関連名称 | Okura Tsuyoshi, Nakamura Risa, Fujioka Yohei, et al. Body mass index >= 23 is a risk factor for insulin resistance and diabetes in Japanese people: A brief report. PLOS ONE. 2018. 13(7). doi:10.1371/journal.pone.0201052 | |||||||||||||||||
| 関連サイト | ||||||||||||||||||
| 識別子タイプ | URI | |||||||||||||||||
| 関連識別子 | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201052 | |||||||||||||||||
| 関連名称 | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201052 | |||||||||||||||||
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| 出版タイプ | VoR | |||||||||||||||||
