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"注があるものを除き、この著作物は日本国著作権法により保護されています。 / This work is protected under Japanese Copyright Law unless otherwise noted.", "licensetype": "license_note", "mimetype": "application/pdf", "size": 1400000.0, "url": {"label": "jyma72(1-4)_1.pdf", "url": "https://repository.lib.tottori-u.ac.jp/record/4306/files/jyma72(1-4)_1.pdf"}, "version_id": "80e8eb60-6a68-4879-b013-a253dc259010"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Gastric cancer", "subitem_subject_scheme": "Other"}, {"subitem_subject": "peritoneal metastasis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "exosome", "subitem_subject_scheme": "Other"}, {"subitem_subject": "microRNA", "subitem_subject_scheme": "Other"}, {"subitem_subject": "biomarker", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Gastric cancer", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "peritoneal metastasis", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "exosome", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "microRNA", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "biomarker", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "胃癌腹水中エクソソームに存在するmicroRNAの 臨床応用に向けた基礎的研究", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "胃癌腹水中エクソソームに存在するmicroRNAの 臨床応用に向けた基礎的研究", "subitem_title_language": "ja"}, {"subitem_title": "Clinical application of exosomal microRNAs in peritoneal fluids of gastric cancer patients with peritoneal metastases", 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  1. 学部学科区分一覧
  2. 医学部・医学系研究科・医学部附属病院
  1. 資料タイプ一覧
  2. 紀要論文
  1. 鳥取大学の刊行物
  2. 米子医学雑誌
  3. 72
  4. 1-4

胃癌腹水中エクソソームに存在するmicroRNAの 臨床応用に向けた基礎的研究

https://repository.lib.tottori-u.ac.jp/records/4306
https://repository.lib.tottori-u.ac.jp/records/4306
18a78cd9-755b-4596-b4d3-8f7510ff77bc
名前 / ファイル ライセンス アクション
jyma72(1-4)_1.pdf jyma72(1-4)_1.pdf (1.4 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2021-11-04
タイトル
言語 ja
タイトル 胃癌腹水中エクソソームに存在するmicroRNAの 臨床応用に向けた基礎的研究
タイトル
言語 en
タイトル Clinical application of exosomal microRNAs in peritoneal fluids of gastric cancer patients with peritoneal metastases
言語
言語 jpn
キーワード
主題 Gastric cancer
キーワード
主題 peritoneal metastasis
キーワード
主題 exosome
キーワード
主題 microRNA
キーワード
主題 biomarker
キーワード
言語 en
主題 Gastric cancer
キーワード
言語 en
主題 peritoneal metastasis
キーワード
言語 en
主題 exosome
キーワード
言語 en
主題 microRNA
キーワード
言語 en
主題 biomarker
資源タイプ
資源タイプ departmental bulletin paper
タイトル(ヨミ)
その他のタイトル イガン フクスイチュウ エクソソーム ニ ソンザイスル microRNA ノ リンショウオウヨウ ニ ムケタ キソテキケンキュウ
言語 ja-Kana
著者 宮谷, 幸造

× 宮谷, 幸造

WEKO 2212
研究者総覧鳥取大学 100001106

宮谷, 幸造

ja-Kana ミヤタニ, コウゾウ

en Miyatani, Kozo

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柗見, 吉朗

× 柗見, 吉朗

WEKO 37547

柗見, 吉朗

ja-Kana マツミ, ヨシアキ

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澤田, 将平

× 澤田, 将平

WEKO 37548

澤田, 将平

ja-Kana サワタ, ショウヘイ

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牧野谷, 真弘

× 牧野谷, 真弘

WEKO 37549

牧野谷, 真弘

ja-Kana マキノヤ, マサヒロ

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宮内, 亘

× 宮内, 亘

WEKO 37550

宮内, 亘

ja-Kana ミヤウチ, ワタル

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宍戸, 裕二

× 宍戸, 裕二

WEKO 4746
研究者総覧鳥取大学 100001960

宍戸, 裕二

ja-Kana シシド, ユウジ

en Shishido, Yuji

Search repository
松永, 知之

× 松永, 知之

WEKO 2048
研究者総覧鳥取大学 100001316

松永, 知之

ja-Kana マツナガ, トモユキ

en Matsunaga, Tomoyuki

Search repository
坂本, 照尚

× 坂本, 照尚

WEKO 3118
研究者総覧鳥取大学 100000935

坂本, 照尚

ja-Kana サカモト, テルヒサ

en Sakamoto, Teruhisa

Search repository
長谷川, 利路

× 長谷川, 利路

WEKO 37551

長谷川, 利路

ja-Kana ハセガワ, トシミチ

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堀江, 享史

× 堀江, 享史

WEKO 37552

堀江, 享史

ja-Kana ホリエ, アツシ

Search repository
藤原, 義之

× 藤原, 義之

WEKO 377
e-Rad 40314330
研究者総覧鳥取大学 100001755

藤原, 義之

ja-Kana フジワラ, ヨシユキ

en Fujiwara, Yoshiyuki

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Matsumi, Yoshiaki

× Matsumi, Yoshiaki

WEKO 37553

en Matsumi, Yoshiaki

ja-Kana マツミ, ヨシアキ

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Sawata, Shohei

× Sawata, Shohei

WEKO 37554

en Sawata, Shohei

ja-Kana サワタ, ショウヘイ

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Makinoya, Masahiro

× Makinoya, Masahiro

WEKO 37555

en Makinoya, Masahiro

ja-Kana マキノヤ, マサヒロ

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Miyauchi, Wataru

× Miyauchi, Wataru

WEKO 37556

en Miyauchi, Wataru

ja-Kana ミヤウチ, ワタル

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Hasegawa, Toshimichi

× Hasegawa, Toshimichi

WEKO 37557

en Hasegawa, Toshimichi

ja-Kana ハセガワ, トシミチ

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Horie, Atsushi

× Horie, Atsushi

WEKO 37558

en Horie, Atsushi

ja-Kana ホリエ, アツシ

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著者所属
鳥取大学医学部 器官制御外科学講座 消化器・小児外科学分野
著者所属
鳥取大学技術部 化学バイオ・生命部門
著者所属
鳥取大学医学部 器官制御外科学講座 消化器・小児外科学分野
著者所属
鳥取大学医学部 器官制御外科学講座 消化器・小児外科学分野
著者所属
鳥取大学医学部 器官制御外科学講座 消化器・小児外科学分野
著者所属
鳥取大学医学部 器官制御外科学講座 消化器・小児外科学分野
著者所属
鳥取大学医学部 器官制御外科学講座 消化器・小児外科学分野
著者所属
鳥取大学医学部 器官制御外科学講座 消化器・小児外科学分野
著者所属
鳥取大学医学部 器官制御外科学講座 消化器・小児外科学分野
著者所属
鳥取大学医学部 電子顕微鏡室
著者所属
鳥取大学医学部 器官制御外科学講座 消化器・小児外科学分野
著者所属(英)
en
Division of Gastrointestinal and Pediatric Surgery, Department of Surgery, School of Medicine
著者所属(英)
en
Division of Chemical Biology, Technical Department, Tottori University
著者所属(英)
en
Division of Gastrointestinal and Pediatric Surgery, Department of Surgery, School of Medicine,  Tottori University Faculty of Medicine
著者所属(英)
en
Division of Gastrointestinal and Pediatric Surgery, Department of Surgery, School of Medicine,  Tottori University Faculty of Medicine
著者所属(英)
en
Division of Gastrointestinal and Pediatric Surgery, Department of Surgery, School of Medicine,  Tottori University Faculty of Medicine
著者所属(英)
en
Division of Gastrointestinal and Pediatric Surgery, Department of Surgery, School of Medicine,  Tottori University Faculty of Medicine
著者所属(英)
en
Division of Gastrointestinal and Pediatric Surgery, Department of Surgery, School of Medicine,  Tottori University Faculty of Medicine
著者所属(英)
en
Division of Gastrointestinal and Pediatric Surgery, Department of Surgery, School of Medicine,  Tottori University Faculty of Medicine
著者所属(英)
en
Division of Gastrointestinal and Pediatric Surgery, Department of Surgery, School of Medicine,  Tottori University Faculty of Medicine
著者所属(英)
en
Laboratory of Electron Microscopy, Tottori University
著者所属(英)
en
Division of Gastrointestinal and Pediatric Surgery, Department of Surgery, School of Medicine,  Tottori University Faculty of Medicine
抄録
内容記述タイプ Other
内容記述 The purpose of this study is to explore the exosomal microRNAs obtained from peritoneal fluids of gastric cancer patients, which are specific for peritoneal metastasis (PM) and could be a predictive marker of disease status in PM. Exosomes were isolated from peritoneal fluids of patients of gastric cancer with PM. Presence of isolated extracellular vesicles (EVs) from peritoneal fluid specimens were confirmed using a transmission electron microscope showed that many EVs were approximately 100 nm in diameter, which were equivalent to exosome fractions. We carried out RNA extraction and comprehensive array analysis of exosomal microRNAs and have identified that 86 microRNAs were significantly up- or down-regulated in all 4 specimens and that out of them, miR-323-3p was highly expressed in all 4 cases. In this way, we have established an experimental system for measuring exosomal microRNAs in peritoneal lavage specimens. Next, we plan to apply this analysis for additional peritoneal lavage specimens obtained from gastric cancer patients with or without PM and to identify specific microRNAs, which could be predictive biomarkers for the disease status of PM in gastric cancer.
書誌情報 ja : 米子医学雑誌
en : The Journal of the Yonago Medical Association

巻 72, 号 1-4, p. 1-5, 発行日 2021-08-31
出版者
出版者 米子医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00440558
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00247383
権利
権利情報 注があるものを除き、この著作物は日本国著作権法により保護されています。 / This work is protected under Japanese Copyright Law unless otherwise noted.
情報源
関連名称 米子医学雑誌. 2021, 72(1-4), 1-5.
関連サイト
識別子タイプ URI
関連識別子 https://mol.medicalonline.jp/library/journal/abstract?GoodsID=eb3yonai/2021/007201/001&name=0001-0005j
関連名称 https://mol.medicalonline.jp/library/journal/abstract?GoodsID=eb3yonai/2021/007201/001&name=0001-0005j
著者版フラグ
出版タイプ VoR
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