| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2018-06-22 |
| タイトル |
|
|
タイトル |
A Case of Nephrotic Syndrome with Nephrotoxicity Induced by Low-Dose Cyclosporin Treatment |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
cyclosporin |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
nephrotic syndrome |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
nephrotoxicity |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
cyclosporin |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
nephrotic syndrome |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
nephrotoxicity |
| 資源タイプ |
|
|
資源タイプ |
journal article |
| 著者 |
Utsunomiya, Yasushi
Konishi, Kyoko
Okada, Shin-ichi
Sasaki, Yoshihiro
Hayashi, Atsushi
Nakagawa, Takako
Kasagi, Tsunakiyo
Shiraki, Kazuo
Utsunomiya, Yasushi
Konishi, Kyoko
Sasaki, Yoshihiro
Hayashi, Atsushi
Nakagawa, Takako
|
| 著者所属 |
|
|
値 |
Department of Pediatrics, Faculty of Medicine, Tottori University |
| 著者所属 |
|
|
値 |
Department of Pediatrics, Faculty of Medicine, Tottori University |
| 著者所属 |
|
|
値 |
Department of Pediatrics, Faculty of Medicine, Tottori University |
| 著者所属 |
|
|
値 |
Department of Pediatrics, Faculty of Medicine, Tottori University |
| 著者所属 |
|
|
値 |
Department of Pediatrics, Faculty of Medicine, Tottori University |
| 著者所属 |
|
|
値 |
Department of Pediatrics, Faculty of Medicine, Tottori University |
| 著者所属 |
|
|
値 |
Department of Nursing, Institute of Medical Care Technology, Tottori University |
| 著者所属 |
|
|
値 |
Department of Pediatrics, Faculty of Medicine, Tottori University |
| 抄録 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
We report a 3-year-old girl with steroid resistant nephrotic syndrome (NS) who developed nephrotoxicity by low-dose cyclosporin (CsA) treatment. Initial prednisolone (PSL) treatment and subsequent additional cyclophosphamide treatment were not successful in leading her into remission. The first renal biopsy finding revealed neither a glomerular nor interstitial change. CsA therapy was initiated in addition to ongoing glucocorticoid therapy at 6 months from the time of onset. Proteinuria disappeared 3 weeks later and the patient went into complete remission. After experiencing the first relapse, the patient was gradually weaned from CsA, and treatment continued with 30 to 50 ng/mL of trough concentration. No elevations of the serum creatinine, serum urea, serum potassium, excretion of urinary β2-microglobulin, or urinary N-acetyl-β-D-glucosaminidase were demonstrated in the follow-up. A second renal biopsy specimen obtained 1 year later showed a tubulo-interstitial change, containing tubular atrophy and interstitial fibrosis, both of which are consistent with the morphological change associated with CsA nephrotoxicity. A follow-up biopsy should be done in order to evaluate the CsA nephrotoxicity, regardless of the treatment dosage. |
| 書誌情報 |
Yonago Acta medica
en : Yonago Acta medica
巻 42,
号 1,
p. 125-130,
発行日 1999-03
|
| 出版者 |
|
|
出版者 |
Tottori University Faculty of Medicine |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
13468049 |
| 書誌レコードID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00892882 |
| 権利 |
|
|
権利情報 |
Yonago Acta medica 編集委員会 |
| 情報源 |
|
|
|
関連名称 |
Yonago Acta medica. 1999, 42(1), 125-130 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
42_125-130.pdf (117.1 kB)
